Effects of simulated high-altitude on appetite and energy intake in young women

Appetite and Energy Intake in Young Female Adults During and After Simulated High-Altitude

Not applicable Interventional University of Ottawa · NCT06912230

This study is testing if spending time in simulated high-altitude conditions affects how much young women want to eat and how much energy they take in.

Quick facts

PhaseNot applicable
Study typeInterventional
Enrollment10 (estimated)
Ages18 Years to 30 Years
SexFemale
SponsorUniversity of Ottawa Academic / other
Locations1 site (Ottawa, Ontario)
Trial IDNCT06912230 on ClinicalTrials.gov

What this trial studies

This clinical trial investigates how acute passive continuous hypoxemia, simulating high-altitude conditions, affects appetite and energy intake in healthy young female adults. Participants will undergo two randomized sessions of six hours each, experiencing either normoxia (sea-level) or hypoxia (simulated altitude of 5000 meters). The study aims to determine if hypoxic exposure reduces appetite and energy intake and whether these effects persist after the exposure ends. Participants will consume food from a curated list in ad libitum quantities during the sessions.

Who should consider this trial

Good fit: Ideal candidates are healthy young female adults who can speak English or French and provide informed consent.

Not a fit: Patients with chronic diseases, those on specific medications, or individuals who are pregnant or have irregular menstrual cycles may not benefit from this study.

Why it matters

Potential benefit: If successful, this study could provide insights into how altitude affects appetite and energy intake, potentially informing dietary recommendations for individuals in high-altitude environments.

How similar studies have performed: While studies on hypoxia and appetite exist, this specific approach focusing on young female adults in a controlled setting is relatively novel.

Eligibility criteria

Show full inclusion / exclusion criteria
Inclusion Criteria:

* English or French speaking
* Ability to provide informed consent

Exclusion Criteria:

* History or evidence of chronic disease
* Current use of hypolipemic medication
* Current use of hormonal contraceptives
* Current use of antidepressants
* Current use of anticoagulants
* Ongoing smoking status
* Experiencing pregnancy, puerperium, or irregular menstrual cycles

Where this trial is running

Ottawa, Ontario

Study contacts

How to participate

  1. Review the eligibility criteria above with your treating physician.
  2. Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
  3. Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.
Conditions HypoxiaAltitudeAppetiteEnergy Intake
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.