Effects of schizophrenia and bipolar disorder on breathing, exercise ability, and quality of life
Official title: Investigation of Exercise Capacity, Pulmonary Function, Respiratory Muscle Strength, and Quality of Life in Patients Diagnosed With Schizophrenia and Bipolar Disorder
Run by Çankırı Karatekin University · NCT07306468 · Data updated 2026-11-12
This project will see how schizophrenia and bipolar disorder relate to breathing strength, lung function, exercise capacity, and quality of life in adults.
Quick facts
| Study type | Observational |
|---|---|
| Ages | 18 Years to 65 Years |
| Sex | All |
| Enrollment | 150 (estimated) |
| Sponsor | Çankırı Karatekin University Academic / other |
| Locations | 1 site (Çankırı, Çankırı) |
| Status | Recruiting |
| Started | November 1, 2025 |
| Main results expected | November 1, 2026 |
| Study ends | December 1, 2026 |
| Registry record updated | December 29, 2025 |
| Trial ID | NCT07306468 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Adults aged 18–65 who have a clinical diagnosis of schizophrenia or bipolar disorder and can attend the single study site are ideal candidates.
✕Probably not a fit
People with active respiratory, cardiac, neurologic, orthopedic conditions or other neuropsychiatric disorders are excluded and likely would not benefit from the study's findings.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
Adults with schizophrenia or bipolar disorder will be recruited at a single center and undergo standardized pulmonary function testing (spirometry), measurements of respiratory muscle strength (eg, maximal inspiratory/expiratory pressures), objective exercise capacity testing, and validated quality-of-life questionnaires. Participants with other respiratory, cardiac, neurologic, orthopedic, or additional neuropsychiatric diagnoses are excluded to isolate effects related to the target diagnoses. Data will be compared to expected normative values to identify physiologic limitations that could inform rehabilitation planning. The observational design does not include an intervention but aims to map cardiorespiratory and functional profiles in this population.
Why it matters
Potential benefit: If patterns of reduced lung or respiratory muscle function are found, the results could guide tailored pulmonary and physical rehabilitation to improve fitness and daily functioning.
How similar studies have gone: Previous studies have reported lower maximal oxygen consumption and reduced exercise capacity in schizophrenia and bipolar disorder, though combined respiratory muscle testing with quality-of-life measures is less commonly reported.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: * Being volunteer for participation * Being 18 to 65 age Exclusion Criteria: * Having any respiratory, cardiac, neurologic or orthopedic disease which may affect respiratory functions or exercise capacity * Having any neuropsychiatric disease except schizophrenia or bipolar disorder
Where it's running
-
Çankırı Karatekin University, Faculty of Health Sciences, Department of Physiotherapy and Rehabilitation
Çankırı, Çankırı, Turkey (Türkiye) Recruiting
Study contacts
- Study coordinator: Furkan Özdemir, PT, Ph.D.
- Email: furkanozdemir@karatekin.edu.tr
- Phone: +905383264855
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How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.