Effects of PRP, PPP, and BMAC on recovery after hip surgery for labral issues
Official title: Effect of Platelet-Rich Plasma, Platelet-Poor Plasma, & Bone Marrow Aspirate Concentrate Application on Functional Outcomes Following Hip Arthroscopy for Acetabular Labral Pathologies: A Prospective Randomized Controlled Trial
Run by Massachusetts General Hospital · NCT06003101 · Data updated 2026-11-12
This study is testing whether treatments like platelet-rich plasma and bone marrow concentrate can help people recover better after hip surgery for labral issues.
Quick facts
| Phase | Phase 3 |
|---|---|
| Study type | Interventional |
| Ages | 18 Years and up |
| Sex | All |
| Enrollment | 160 (estimated) |
| Sponsor | Massachusetts General Hospital Academic / other |
| Locations | 1 site (Boston, Massachusetts) |
| Status | Recruiting |
| Started | August 30, 2023 |
| Main results expected | August 30, 2027 |
| Study ends | August 30, 2045 |
| Registry record updated | November 20, 2024 |
| Trial ID | NCT06003101 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Ideal candidates are adults aged 18 and older who require hip arthroscopy for labral pathology.
✕Probably not a fit
Patients who have had prior surgeries on the same hip or are non-English speakers may not benefit from this study.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
This clinical trial evaluates the impact of platelet-rich plasma (PRP), platelet-poor plasma (PPP), and bone marrow aspirate concentrate (BMAC) on functional recovery following hip arthroscopy for acetabular labral pathologies. The study aims to determine whether these treatments can enhance functional outcomes and reduce arthritic symptoms post-surgery. Participants will be randomly assigned to receive either the treatment or a control, with outcomes measured through validated functional assessments. The trial is designed to provide insights into optimizing surgical management of labral injuries.
Why it matters
Potential benefit: If successful, this study could lead to improved recovery and reduced pain for patients undergoing hip arthroscopy for labral pathologies.
How similar studies have gone: Previous studies have shown promising results with similar regenerative approaches, suggesting potential for success in this trial.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: * Age: \> or equal to 18 years * Clinically indicated for hip arthroscopy (by the study PI) to address a labral pathology * Willingness to participate, amenable to randomization into either treatment arm of the research study, and the ability to understand \& sign the informed consent document Exclusion Criteria: * Non-English speaking (PROM surveys are only validated in English) * Prior same site (i.e., ipsilateral hip) surgery, including but not limited to previous hip arthroscopy, core decompression, or periacetabular osteotomies
Where it's running
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Massachusetts General Hospital
Boston, Massachusetts, United States Recruiting
Study contacts
- Principal investigator: Scott D. Martin, MD — Massachusetts General Hospital
- Study coordinator: Scott D. Martin, MD
- Email: sdmartin@mgh.harvard.edu
- Phone: 617-732-5329
Similar studies
Other studies for the same condition or treatment. Recruiting studies are listed first.
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Using bone marrow concentrate with hip arthroscopy for labral tears and impingement
This study is testing whether using bone marrow concentrate during hip surgery can help people with labral tears and hip impingement feel better and prevent further joint problems.
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This trial tests whether adding a bone marrow aspirate concentrate injection during lumbar microdiscectomy helps adults recover better than surgery alone.
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MACI versus bone marrow stimulation for symptomatic ankle cartilage defects in people 17–65
This treatment comparison tests whether MACI (your own cultured cartilage cells on a collagen membrane) works better than bone marrow stimulation for people aged 17 to 65 with symptomatic cartilage defects of the talus.
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Using knotless implants for hip capsule closure during surgery
This study tests if a new knotless device for closing the hip capsule during surgery can help patients recover better than traditional knotted sutures.
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Using concentrated bone marrow to improve outcomes in knee surgery
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How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.