Effects of pistachio consumption on inflammation and body composition
Effects of Pistachio Consumption on Inflammatory Markers and Lean Body Mass in Recreationally Active Women and Men
This study tests if eating 1.5 ounces of pistachios every day can help reduce inflammation and improve body composition in active adults aged 40 to 60.
Quick facts
| Phase | Not applicable |
|---|---|
| Study type | Interventional |
| Enrollment | 144 (estimated) |
| Ages | 40 Years to 60 Years |
| Sex | All |
| Sponsor | Virginia Polytechnic Institute and State University Academic / other |
| Drugs / interventions | radiation |
| Locations | 1 site (Blacksburg, Virginia) |
| Trial ID | NCT06342024 on ClinicalTrials.gov |
What this trial studies
This study evaluates the impact of consuming 1.5 ounces of pistachios daily on inflammatory markers and lean body mass in adults aged 40 to 60 who exercise regularly. Participants will undergo a two-week baseline period followed by random assignment to either the pistachio group or a control group for six months. The study aims to measure changes in various inflammatory markers and body composition metrics. The intervention is designed to assess whether adding pistachios to a typical diet can yield health benefits without causing weight gain.
Who should consider this trial
Good fit: Ideal candidates are healthy men and women aged 40 to 60 who exercise three to five days a week and are not on a weight loss program.
Not a fit: Patients who are allergic to nuts or those who do not exercise regularly may not benefit from this study.
Why it matters
Potential benefit: If successful, this study could provide insights into dietary interventions that reduce inflammation and improve body composition.
How similar studies have performed: Previous studies have indicated potential health benefits of nut consumption, including pistachios, but this specific approach is novel.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: 1. women and men, 40 to 60 years of age 2. exercise three to five days a week for at least the past six months 3. non-smokers 4. not be on an active weight loss program at the start of the study or any time during the study 5. willing to maintain and not change their usual exercise habits 6. willing to consume pistachios as part of their diet (should they be randomized into the pistachio group) Exclusion Criteria: 1. unwilling to sign the informed consent document 2. not exercising regularly, three to five times per week for at least the past six months 3. physician states that they are not able to participate in the study 4. already consuming one or more ounces of pistachios several times a week 5. smoker 6. pregnant or lactating women 7. anyone who has a nut allergy
Where this trial is running
Blacksburg, Virginia
- Virginia Polytechnic Institute and State University — Blacksburg, Virginia, United States (Recruiting)
Study contacts
- Principal investigator: Stella L Volpe, PhD — Virginia Polytechnic Institute and State University
- Study coordinator: Stella L Volpe, PhD
- Email: stellalv@vt.edu
- Phone: 540-231-3805
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.