Effects of partial sleep deprivation on heart function during cycling
Effects of Partial Sleep Deprivation on Cardiac Output During Cycling
This study is testing how not getting enough sleep affects heart function and blood pressure during cycling in young healthy adults, while also looking for differences between men and women.
Quick facts
| Phase | Not applicable |
|---|---|
| Study type | Interventional |
| Enrollment | 30 (estimated) |
| Ages | 18 Years to 50 Years |
| Sex | All |
| Sponsor | University of Guelph Academic / other |
| Locations | 1 site (Guelph, Ontario) |
| Trial ID | NCT06679543 on ClinicalTrials.gov |
What this trial studies
This clinical trial aims to investigate how partial sleep deprivation affects cardiac output and blood pressure during cycling exercise in young healthy adults, with a focus on potential sex differences. Participants will undergo testing after a night of normal sleep and after a night of reduced sleep, performing exercise on a cycle ergometer while their hemodynamics and plasma volume are monitored. The study seeks to understand whether reductions in plasma volume contribute to changes in cardiac output and blood pressure, particularly examining differences between males and females.
Who should consider this trial
Good fit: Ideal candidates are young healthy adults aged 18-30, free from cardiovascular or metabolic diseases, and not currently taking chronic medications.
Not a fit: Patients with existing cardiovascular or metabolic diseases, sleep disorders, or those who are pregnant will not benefit from this study.
Why it matters
Potential benefit: If successful, this study could provide insights into how sleep deprivation impacts cardiovascular health during physical activity, potentially guiding recommendations for exercise in sleep-deprived individuals.
How similar studies have performed: While there is limited research specifically on the effects of partial sleep deprivation on cardiac output during exercise, related studies have shown significant impacts of sleep deprivation on cardiovascular responses, suggesting this approach may yield valuable insights.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * Free of known cardiovascular or metabolic diseases or sleep disorders * No history of smoking (within the past 3 months) * Able to engage in physical activity assessed through the physical activity readiness questionnaire (PAR-Q+) * No prescription of chronic medications other than oral contraceptives * Able to abide by sleep protocols for all visits * Individuals who are not allergic to ultrasound gel * Individuals who are not pregnant Exclusion Criteria: * Individuals diagnosed with cardiovascular or metabolic disease or sleep disorders * Has a history of smoking (within the past 3 months) * Not ready to engage in physical activity as assessed by the PAR-Q+ * Individuals prescribed chronic medications other than oral contraceptives * Unable to abide by sleep protocols for any testing visit * Allergic to ultrasound gel * Pregnancy
Where this trial is running
Guelph, Ontario
- University of Guelph — Guelph, Ontario, Canada (Recruiting)
Study contacts
- Principal investigator: Philip Millar, PhD — University of Guelph
- Study coordinator: Julian Bommarito, MSc
- Email: jbomma01@uoguelph.ca
- Phone: 9052209829
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.