Effects of Panax Ginseng on Liver Function in Adults
Effect of Panax Ginseng C.A. Mey Extract on Liver Function in Adults: a Randomized, Double-blinded, Placebo-controlled Trial
NA · Pusan National University Yangsan Hospital · NCT03775837
This study is testing if taking Panax Ginseng can help improve liver health in adults with mild liver function issues.
Quick facts
| Phase | NA |
|---|---|
| Study type | Interventional |
| Enrollment | 60 (estimated) |
| Ages | 19 Years to 75 Years |
| Sex | All |
| Sponsor | Pusan National University Yangsan Hospital (other) |
| Locations | 1 site (Yangsan) |
| Trial ID | NCT03775837 on ClinicalTrials.gov |
What this trial studies
This study investigates the effects of Panax Ginseng C.A. Mey Extract on liver function in adults through a randomized, double-blind, placebo-controlled design. Over the course of 8 weeks, participants will receive either 600 mg of the extract or a placebo daily. The study aims to evaluate changes in liver function markers such as AST, ALT, and GGT, as well as assess the safety of the extract. The results will help determine if Panax Ginseng can improve liver health in individuals with mild liver function impairment.
Who should consider this trial
Good fit: Ideal candidates are adults with ALT levels ranging from the upper limit of reference to three times the upper limit.
Not a fit: Patients with significant liver or renal dysfunction, diabetes, or a history of serious cardiac disease may not benefit from this study.
Why it matters
Potential benefit: If successful, this study could provide a natural treatment option to improve liver function in adults with mild liver impairment.
How similar studies have performed: Previous studies have suggested potential benefits of Panax Ginseng for liver function, but this specific approach is being tested for the first time.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * ALT ranging from upper limit of reference to three times of upper limit Exclusion Criteria: * Abnormal liver or renal function (i.e., serum aminotransferase activity \> 3 times of upper limit of reference range and serum creatinine concentrations \> 1.2 mg/dL) * Diabetes (diagnosed clinically or fasting glucose level \> 126 mg/dL) * History of viral hepatitis or cancer * Uncontrolled hypertension * History of serious cardiac disease such as angina or myocardial infarction * History of gastrectomy * History of medication for psychiatric disease * Administration of oriental medicine including herbs within the past 4 weeks
Where this trial is running
Yangsan
- Integrated Research Institute for Natural Ingredients and Functional Foods — Yangsan, South Korea (RECRUITING)
Study contacts
- Principal investigator: Sang Yeoup Lee — Pusan National University Yangsan Hospital
- Study coordinator: Sang Yeoup Lee
- Email: saylee@pnu.edu
- Phone: 360-2860
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.
Conditions: Liver Diseases