Effects of Panax Ginseng on Liver Function in Adults
Official title: Effect of Panax Ginseng C.A. Mey Extract on Liver Function in Adults: a Randomized, Double-blinded, Placebo-controlled Trial
Run by Pusan National University Yangsan Hospital · NCT03775837 · Data updated 2026-11-12
This study is testing if taking Panax Ginseng can help improve liver health in adults with mild liver function issues.
Quick facts
| Study type | Interventional |
|---|---|
| Ages | 19 Years to 75 Years |
| Sex | All |
| Enrollment | 60 (estimated) |
| Sponsor | Pusan National University Yangsan Hospital Academic / other |
| Locations | 1 site (Yangsan) |
| Status | Recruiting |
| Started | December 1, 2018 |
| Main results expected | December 30, 2025 |
| Study ends | December 31, 2025 |
| Registry record updated | June 4, 2025 |
| Trial ID | NCT03775837 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Ideal candidates are adults with ALT levels ranging from the upper limit of reference to three times the upper limit.
✕Probably not a fit
Patients with significant liver or renal dysfunction, diabetes, or a history of serious cardiac disease may not benefit from this study.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
This study investigates the effects of Panax Ginseng C.A. Mey Extract on liver function in adults through a randomized, double-blind, placebo-controlled design. Over the course of 8 weeks, participants will receive either 600 mg of the extract or a placebo daily. The study aims to evaluate changes in liver function markers such as AST, ALT, and GGT, as well as assess the safety of the extract. The results will help determine if Panax Ginseng can improve liver health in individuals with mild liver function impairment.
Why it matters
Potential benefit: If successful, this study could provide a natural treatment option to improve liver function in adults with mild liver impairment.
How similar studies have gone: Previous studies have suggested potential benefits of Panax Ginseng for liver function, but this specific approach is being tested for the first time.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: * ALT ranging from upper limit of reference to three times of upper limit Exclusion Criteria: * Abnormal liver or renal function (i.e., serum aminotransferase activity \> 3 times of upper limit of reference range and serum creatinine concentrations \> 1.2 mg/dL) * Diabetes (diagnosed clinically or fasting glucose level \> 126 mg/dL) * History of viral hepatitis or cancer * Uncontrolled hypertension * History of serious cardiac disease such as angina or myocardial infarction * History of gastrectomy * History of medication for psychiatric disease * Administration of oriental medicine including herbs within the past 4 weeks
Where it's running
-
Integrated Research Institute for Natural Ingredients and Functional Foods
Yangsan, South Korea Recruiting
Study contacts
- Principal investigator: Sang Yeoup Lee — Pusan National University Yangsan Hospital
- Study coordinator: Sang Yeoup Lee
- Email: saylee@pnu.edu
- Phone: 360-2860
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How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.