Clinical trial Recruiting at 1 site Interventional Ages 19 to 75

Effects of Panax Ginseng on Liver Function in Adults

Official title: Effect of Panax Ginseng C.A. Mey Extract on Liver Function in Adults: a Randomized, Double-blinded, Placebo-controlled Trial

Run by Pusan National University Yangsan Hospital · NCT03775837 · Data updated 2026-11-12

This study is testing if taking Panax Ginseng can help improve liver health in adults with mild liver function issues.

Quick facts

Study typeInterventional
Ages19 Years to 75 Years
SexAll
Enrollment60 (estimated)
SponsorPusan National University Yangsan Hospital
Academic / other
Locations1 site (Yangsan)
StatusRecruiting
StartedDecember 1, 2018
Main results expectedDecember 30, 2025
Study endsDecember 31, 2025
Registry record updatedJune 4, 2025
Trial IDNCT03775837 on ClinicalTrials.gov

Is this trial a fit for you?

Likely a good fit

Ideal candidates are adults with ALT levels ranging from the upper limit of reference to three times the upper limit.

Probably not a fit

Patients with significant liver or renal dysfunction, diabetes, or a history of serious cardiac disease may not benefit from this study.

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This study investigates the effects of Panax Ginseng C.A. Mey Extract on liver function in adults through a randomized, double-blind, placebo-controlled design. Over the course of 8 weeks, participants will receive either 600 mg of the extract or a placebo daily. The study aims to evaluate changes in liver function markers such as AST, ALT, and GGT, as well as assess the safety of the extract. The results will help determine if Panax Ginseng can improve liver health in individuals with mild liver function impairment.

Why it matters

Potential benefit: If successful, this study could provide a natural treatment option to improve liver function in adults with mild liver impairment.

How similar studies have gone: Previous studies have suggested potential benefits of Panax Ginseng for liver function, but this specific approach is being tested for the first time.

Who can join: the full rules

Show full inclusion / exclusion criteria
Inclusion Criteria:

* ALT ranging from upper limit of reference to three times of upper limit

Exclusion Criteria:

* Abnormal liver or renal function (i.e., serum aminotransferase activity \> 3 times of upper limit of reference range and serum creatinine concentrations \> 1.2 mg/dL)
* Diabetes (diagnosed clinically or fasting glucose level \> 126 mg/dL)
* History of viral hepatitis or cancer
* Uncontrolled hypertension
* History of serious cardiac disease such as angina or myocardial infarction
* History of gastrectomy
* History of medication for psychiatric disease
* Administration of oriental medicine including herbs within the past 4 weeks

Where it's running

  • Integrated Research Institute for Natural Ingredients and Functional Foods
    Yangsan, South Korea
    Recruiting

Study contacts

  • Principal investigator: Sang Yeoup Lee — Pusan National University Yangsan Hospital
  • Study coordinator: Sang Yeoup Lee
  • Email: saylee@pnu.edu
  • Phone: 360-2860

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How to take part

  1. Review the eligibility criteria above with your treating physician.
  2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
  3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.