Effects of Pain Neuroscience Education on Carpal Tunnel Syndrome

Effects of Pain Neuroscience Education and Standard Rehabilitation Regime in Patients of Carpal Tunnel Syndrome

Not applicable Interventional Riphah International University · NCT06509633

This study is testing if adding Pain Neuroscience Education to regular rehab helps people with Carpal Tunnel Syndrome feel better and recover faster than just rehab alone.

Quick facts

PhaseNot applicable
Study typeInterventional
Enrollment30 (estimated)
Ages20 Years to 50 Years
SexFemale
SponsorRiphah International University Academic / other
Locations1 site (Lahore, Punjab Province)
Trial IDNCT06509633 on ClinicalTrials.gov

What this trial studies

This study investigates the impact of Pain Neuroscience Education (PNE) combined with standard rehabilitation on patients suffering from Carpal Tunnel Syndrome (CTS). It aims to determine whether PNE can enhance recovery and pain relief compared to standard rehabilitation alone. The study involves a randomized, double-blind design where participants will receive either PNE plus rehabilitation exercises or rehabilitation exercises only. The goal is to provide high-quality evidence on the effectiveness of this combined approach for CTS management.

Who should consider this trial

Good fit: Ideal candidates are individuals aged 20 to 40 years with a medical diagnosis of moderate to severe Carpal Tunnel Syndrome and symptoms present for at least one month.

Not a fit: Patients with neurological conditions affecting the central nervous system or those who have undergone previous surgery on the affected upper limb may not benefit from this study.

Why it matters

Potential benefit: If successful, this study could lead to improved pain management and functional recovery for patients with Carpal Tunnel Syndrome.

How similar studies have performed: Previous studies have shown positive results with similar approaches, indicating potential effectiveness, although more research is needed in this specific area.

Eligibility criteria

Show full inclusion / exclusion criteria
Inclusion Criteria:

* age between 20\_40 years old.
* Medical diagnosis of moderate to severe CTS.
* Symptoms of CTS since 1month
* Unilateral or bilateral symptoms
* Availability and access to the hospital.

Exclusion Criteria:

* Inability to understand instructions, neurological conditions of the central nervous system (e.g. stroke, spinal cord injury)
* Patients on treatment with alternative therapies
* Previous participation in a research program
* Previous surgery on the affected upper limb

Where this trial is running

Lahore, Punjab Province

Study contacts

How to participate

  1. Review the eligibility criteria above with your treating physician.
  2. Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
  3. Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.
Conditions Wrist InjuriesCarpal Tunnel SyndromeCarpal tunnel syndromeCompressionPain neuroscience educationMedian nerve
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.