Effects of omega-3 and whey protein on muscle mass in older adults

Effects of Omega-3 and Whey Protein Supplementation on Lean Mass and Strength Gains in Older Adults Performing Resistance Exercise: A Randomized, Double-Blind and Placebo-Controlled Study

Not applicable Interventional Federal University of Uberlandia · NCT05862779

This study tests if taking omega-3 and whey protein together can help older adults build muscle and strength while they do resistance exercises.

Quick facts

PhaseNot applicable
Study typeInterventional
Enrollment80 (estimated)
Ages60 Years to 85 Years
SexFemale
SponsorFederal University of Uberlandia Academic / other
Locations1 site (Uberlândia, Minas Gerais)
Trial IDNCT05862779 on ClinicalTrials.gov

What this trial studies

This study evaluates how omega-3 supplementation combined with whey protein intake affects lean mass and strength in older adults participating in resistance exercise. Participants will be randomly assigned to one of four groups: a placebo group, an omega-3 plus placebo group, a whey protein plus placebo group, and an omega-3 plus whey protein group. Each group will follow the same exercise protocol for 12 weeks while receiving their respective supplements. The goal is to determine the effectiveness of these supplements in enhancing muscle mass and strength.

Who should consider this trial

Good fit: Ideal candidates are postmenopausal women who can perform strength exercises and have no significant health complications.

Not a fit: Patients with diagnosed diseases such as type II diabetes, cancer, or cardiovascular issues may not benefit from this study.

Why it matters

Potential benefit: If successful, this study could help improve muscle mass and strength in older adults, potentially reducing the risk of sarcopenia.

How similar studies have performed: Other studies have shown positive effects of omega-3 and protein supplementation on muscle health, suggesting this approach may be effective.

Eligibility criteria

Show full inclusion / exclusion criteria
Inclusion Criteria:

* Postmenopausal women (at least 1 year of menstrual interruption, self-reported);
* To be able to practice strength exercises;
* To be able to carry out supplementation;
* Do not present physical, orthopedic or cardiovascular complications that prevent the performance of physical exercises;
* No history of stroke or acute myocardial infarction;
* Not being a smoker and/or alcoholic;
* Do not perform hormone replacement therapy;
* Do not use anti-inflammatory drugs;
* To have normal kidney function;
* To submit a medical certificate of health that proves that the individual is able to perform exercises.

Exclusion Criteria:

* Do not provide the necessary information for the development of the study;
* Individuals with diseases previously diagnosed and undergoing treatment, such as type II diabetes mellitus, cancer, rheumatoid arthritis, high blood pressure, dyslipidemia, cardiovascular, and kidney and/or liver diseases.

Where this trial is running

Uberlândia, Minas Gerais

Study contacts

How to participate

  1. Review the eligibility criteria above with your treating physician.
  2. Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
  3. Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.
Conditions Sarcopenia
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.