Effects of nicotine product claims on perceptions and behavior

Human Laboratory Study of the Effects of Nicotine Product Claims on Appeal, Perceptions, and Use Behavior

Not applicable Interventional Ohio State University Comprehensive Cancer Center · NCT06192316

This study tests how different claims about nicotine in oral nicotine pouches affect how young adults and tobacco users think and act towards these products.

Quick facts

PhaseNot applicable
Study typeInterventional
Enrollment450 (estimated)
Ages18 Years to 65 Years
SexAll
SponsorOhio State University Comprehensive Cancer Center Academic / other
Locations1 site (Columbus, Ohio)
Trial IDNCT06192316 on ClinicalTrials.gov

What this trial studies

This study evaluates how different claims about nicotine concentration and sources affect young adults and adult tobacco users' perceptions and behaviors towards oral nicotine pouches (ONPs). Participants will engage in a laboratory setting where they will view randomized images of ONP packaging and complete various assessments, including psychophysiological tests and questionnaires. The primary objectives are to understand the impact of these claims on engagement with the product and self-reported behavioral intentions regarding ONPs.

Who should consider this trial

Good fit: Ideal candidates include young adults aged 18-24 who are susceptible non-users of tobacco and adults aged 18-65 who are current tobacco users.

Not a fit: Patients who are not susceptible to nicotine use or are outside the age range of 18-65 will not benefit from this study.

Why it matters

Potential benefit: If successful, this study could provide insights into how nicotine product marketing influences behavior, potentially informing public health strategies for tobacco control.

How similar studies have performed: Other studies have explored the effects of tobacco product marketing on behavior, suggesting that this approach could yield valuable insights.

Eligibility criteria

Show full inclusion / exclusion criteria
Inclusion Criteria:

* Young adult susceptible non-users aged 18-24 who have never used ONPs and have never used but are susceptible to using either:

  * combustible tobacco only (cigarettes, cigars, waterpipe)
  * non-combustible tobacco only (ST, ECs, heated tobacco products)
  * or both combustible and non-combustible tobacco (i.e., dual susceptibility)
* Adult tobacco users aged 18-65 who have never used ONPs OR have used ONPs \>3 months ago and 10 times or less in their lifetime. All adult tobacco users must also be:

  * exclusive combustible tobacco users
  * exclusive non-combustible tobacco users
  * dual users

    * For adult tobacco users, we will define current use as use of combustible and/or non-combustible tobacco every day or some days for 6 months or longer
* Willing and able to complete an in-person lab visit.

Exclusion Criteria:

* Age \< 18 or \> 65
* Are not susceptible non-users or current tobacco users
* Are unwilling or unable to complete and in person lab visit.
* Have used ONPs within the past 3 months
* Have used ONPs more than 10 times in their lifetime

Where this trial is running

Columbus, Ohio

Study contacts

How to participate

  1. Review the eligibility criteria above with your treating physician.
  2. Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
  3. Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.
Conditions Behavior, Riskoral nicotine pouchcancer controlcancer prevention
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.