Effects of melatonin on anxiety and sleep quality after heart surgery
The Effect of Melatonin on Anxiety and Sleep Quality in the Peri-Operative Course of Adults Undergoing Coronary Artery Bypass Graft Surgery: Prospective Randomized Controlled Study
NA · Ain Shams University · NCT06237556
This study is testing if melatonin can help adults feel less anxious and sleep better after heart surgery.
Quick facts
| Phase | NA |
|---|---|
| Study type | Interventional |
| Enrollment | 30 (estimated) |
| Ages | 40 Years to 60 Years |
| Sex | All |
| Sponsor | Ain Shams University (other) |
| Locations | 1 site (Cairo) |
| Trial ID | NCT06237556 on ClinicalTrials.gov |
What this trial studies
This study evaluates the impact of melatonin on sleep quality, anxiety levels, and opioid requirements in adults undergoing coronary artery bypass graft (CABG) surgery. It addresses the common issue of sleep disturbances that patients experience post-surgery, which can significantly affect their recovery and quality of life. The study involves administering either melatonin or a placebo to participants and monitoring their outcomes during the postoperative period. The research aims to determine if melatonin can improve sleep and reduce anxiety in this patient population.
Who should consider this trial
Good fit: Ideal candidates are adults aged 40-60 who are scheduled for standard on-pump CABG surgery.
Not a fit: Patients with a history of sleep disorders, severe respiratory or circulatory diseases, or those taking certain psychiatric medications may not benefit from this study.
Why it matters
Potential benefit: If successful, this study could lead to improved sleep quality and reduced anxiety for patients recovering from CABG surgery.
How similar studies have performed: While the use of melatonin for sleep issues is well-documented, this specific application in CABG patients is relatively novel and has not been extensively tested.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * Age from 40-60 years. * Both sexes. * Patients undergoing standard on-pump CABG with the same technique by the same surgical team. Exclusion Criteria: * Refusal of procedure or participation in the study by patients. * Patients with known history of allergy to one of study drugs * Patients taking psychiatric medications, CNS depressants, and hypnotic drugs. * Patients with neurological disorders stroke, intracranial hemorrhage and surgery. * Patients with a history of suffering from any sleep disorder. * Severe circulatory or respiratory disease. * Patients with obstructive sleep apnea. * Cognitive or psychiatric illness that leads to inability to cooperate, speak or provide informed consent
Where this trial is running
Cairo
- Ain Shams University — Cairo, Egypt (RECRUITING)
Study contacts
- Study coordinator: Ahmed A Bayoumi, Master
- Email: ahmed.ashraf@med.asu.edu.eg
- Phone: 00201096533952
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.
Conditions: Melatonin, Anxiety, Sleep Quality, Coronary Artery Bypass Graft