Effects of magnetic stimulation on phantom limb pain in amputees

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This study investigates the use of peripheral magnetic stimulation (PMS) to create somatosensory sensations and analyze brain bioelectric signals in both healthy individuals and those with upper limb amputations. Participants will undergo PMS with varying magnetic pulse intensities while their subjective sensations and EEG activity are recorded. The study aims to evaluate the continuous PMS stimulation protocol's effects on phantom sensations, with the goal of future clinical application.

Why it matters

Who can join: the full rules

For Healthy Volunteers:

Inclusion Criteria:

1. Availability of signed written informed consent.
2. Absence of somatic and psychiatric diseases (more details in the exclusion criteria)
3. Ability and willingness to comply with the requirements of this protocol. Inclusion Criteria

Exclusion Criteria:

1. History of epilepsy (participant, participant's close relatives)
2. Presence of metal or/and electric stimulators and/or implants in participant's body
3. Presence of psychiatric disorders (including a history of), severe depression, suicidal tendencies, or a history of suicide attempts.
4. History of cancer.
5. Complicated traumatic brain injury (TBI) or a history of stroke.
6. Drug addiction (including a history of).
7. Congenital anomaly of upper limb development.
8. Anomalies in the development of the central and peripheral nervous systems.
9. Pregnancy

For stroke patients:

1. History of epilepsy (participant, participant's close relatives)
2. Presence of metal or/and electric stimulators and/or implants in participant's body
3. Presence of psychiatric disorders (including a history of), severe depression, suicidal tendencies, or a history of suicide attempts.
4. History of cancer.
5. Complicated traumatic brain injury (TBI) or a history of stroke.
6. Drug addiction (including a history of).
7. Congenital anomaly of upper limb development.
8. Anomalies in the development of the central and peripheral nervous systems.
9. Pregnancy
10. Presence of severe somatic pathology
11. Presence of severe orthopedic deformity in the limb above the level of amputation.
12. Purulent-septic pathology.

Where it's running

• Skolkovo Institute of Science and Technology (Skoltech)
  Moscow, Russia Recruiting

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

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• Evaluating a neuroprosthesis to reduce phantom limb pain and improve quality of life

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• Neuromodulation for relieving phantom limb pain

  This study is testing different ways to use electrical stimulation to help people who have had a limb amputated and are suffering from phantom limb pain feel better.

  Recruiting at 2 sites Skolkovo Institute of Science and Technology · Moscow, Moscow and 1 other locations · NCT06644807

• Treatment for phantom limb pain using visual simulation therapy

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• Reducing phantom limb pain in amputees

  This study is testing two different rehabilitation programs to see which one helps amputees with phantom limb pain feel better.

  Recruiting Neuroscience Research Australia · Randwick, New South Wales · NCT06167330

How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.