Effects of Lingual Endurance Exercise on Swallowing After Stroke
Official title: Impact of Lingual Endurance Exercise on Rehabilitation of Swallowing Impairments After Ischemic Stroke
Run by University of Cincinnati · NCT06072924 · Data updated 2026-11-12
This study is testing a new tongue exercise to see if it can help people who have trouble swallowing after a stroke.
Quick facts
| Study type | Interventional |
|---|---|
| Ages | 18 Years and up |
| Sex | All |
| Enrollment | 70 (estimated) |
| Sponsor | University of Cincinnati Academic / other |
| Locations | 1 site (Cincinnati, Ohio) |
| Status | Recruiting |
| Started | September 1, 2023 |
| Main results expected | August 31, 2027 |
| Study ends | August 31, 2028 |
| Registry record updated | September 4, 2026 |
| Trial ID | NCT06072924 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Ideal candidates are English-speaking adults aged 19 years and older who are 3-6 months post-ischemic stroke and experiencing ongoing swallowing issues.
✕Probably not a fit
Patients with a history of dysphagia prior to the stroke or other neurological diseases may not benefit from this study.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
This pilot trial investigates the impact of a novel lingual endurance exercise on swallowing function in individuals who have experienced dysphagia following an ischemic stroke. Participants will engage in either the lingual endurance exercise or a sham exercise, with the primary aim of assessing improvements in oral swallow physiology. Additionally, the study will collect MRI data to explore changes in white matter tract diffusion and cortical thickness, contributing to our understanding of neuroplasticity related to swallowing rehabilitation. The findings will inform future larger-scale intervention trials aimed at optimizing therapy delivery for better recovery outcomes.
Why it matters
Potential benefit: If successful, this study could significantly improve swallowing function and quality of life for patients recovering from stroke-related dysphagia.
How similar studies have gone: While the specific approach of lingual endurance exercise is novel, similar rehabilitation strategies have shown promise in improving swallowing function in other studies.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: * 1\) 3-6 months since most recent diagnosis of ischemic, confirmed from clinical imaging) with or without small hemorrhagic transformation (HI-1) * 2\) English Speaking Exclusion Criteria: * 1\) ≤18 years of age * 2\) history of dysphagia prior to or after the stroke caused by any of the following conditions: gastrointestinal disease, traumatic brain injury, head and neck cancer, surgery involving the pharynx or larynx * 3\) history of other neurological disease (i.e. multiple sclerosis, ALS, Parkinson's, dementia). 5\) 5) History of temporomandibular joint and muscle disorders (also known as TMJ).
Where it's running
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University of Cincinnati
Cincinnati, Ohio, United States Recruiting
Study contacts
- Principal investigator: Brittany N Krekeler, PhD — University of Cincinnati
- Study coordinator: Anna Hopkins, MS
- Email: hopkiak@ucmail.uc.edu
- Phone: +1 513 558 4152
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How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.