Effects of leucine and fatty acids on muscle health in older adults
Explore the Effects of Nutritional Supplementation of Leucine and Polyunsaturated Fatty Acids on Muscle Health in the Elderly
This study is testing if adding leucine-rich protein and healthy fats to the diets of older adults can help improve their muscle health and strength.
Quick facts
| Phase | Not applicable |
|---|---|
| Study type | Interventional |
| Enrollment | 90 (estimated) |
| Ages | 50 Years to 99 Years |
| Sex | All |
| Sponsor | Chang Gung Memorial Hospital Academic / other |
| Locations | 1 site (Linkou District) |
| Trial ID | NCT06991855 on ClinicalTrials.gov |
What this trial studies
This interventional study investigates how nutritional supplementation with leucine-rich protein and polyunsaturated fatty acids can improve muscle health in middle-aged and elderly individuals aged 50 and above who are at high risk for sarcopenia. Participants will be divided into two groups receiving either animal-based or plant-based oil supplements. The study aims to assess changes in muscle mass and strength, which are critical for maintaining mobility and overall health in the aging population. By focusing on this demographic, the study addresses a significant public health concern as Taiwan approaches a super-aged society.
Who should consider this trial
Good fit: Ideal candidates for this study are individuals aged 50 and older who exhibit signs of muscle weakness or low muscle mass.
Not a fit: Patients with allergies to the supplements, or those with serious health conditions such as cancer, heart failure, or neurodegenerative diseases may not benefit from this study.
Why it matters
Potential benefit: If successful, this study could enhance muscle health and functional capacity in elderly individuals, potentially reducing the risk of sarcopenia-related complications.
How similar studies have performed: Other studies have shown promising results with nutritional supplementation for muscle health in older adults, indicating that this approach has potential for success.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * Age ≥ 50 years * ASMI \< 7 kg/m2 in men * ASMI \< 5.7 kg/m2 in women * Grip strength \< 28 kg in men * Grip strength \< 18 kg in women * Walk speed \< 1 m/s Exclusion Criteria: * People who are allergic to supplements * cancer * heart failure * kidney disease * autoimmune disease * neurodegenerative disease
Where this trial is running
Linkou District
- Chang Gung Memorial Hospital — Linkou District, Taiwan (Recruiting)
Study contacts
- Study coordinator: Hsiang-Yu Tang, Ph.D.
- Email: tangshyu@cgu.edu.tw
- Phone: +886-3-2118800
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.