Effects of Lactobacillus johnsonii and White Pomegranate Extract on Vaginal Health
Official title: Effect of Oral Probiotic Heat-killed Lactobacillus Johnsonii TCI250 or White Pomegranate Extract on the Vaginal Flora
Run by Chung Shan Medical University · NCT06069531 · Data updated 2026-11-12
This study is testing if a probiotic and white pomegranate extract can improve vaginal health for women dealing with bacterial vaginitis and inflammation.
Quick facts
| Study type | Interventional |
|---|---|
| Ages | 20 Years to 45 Years |
| Sex | Women only |
| Enrollment | 150 (estimated) |
| Sponsor | Chung Shan Medical University Academic / other |
| Locations | 1 site (Taichung) |
| Status | Recruiting |
| Started | April 4, 2022 |
| Main results expected | December 31, 2025 |
| Study ends | December 31, 2025 |
| Registry record updated | May 14, 2025 |
| Trial ID | NCT06069531 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Ideal candidates for this study are females aged 20-45 with a Nugent score of 4 or higher.
✕Probably not a fit
Patients who are pregnant, lactating, or have other reproductive-related inflammatory diseases may not benefit from this study.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
This clinical trial investigates the impact of Lactobacillus johnsonii TCI250 probiotics and white pomegranate extract on female vaginal health, specifically targeting bacterial vaginitis and inflammation. A total of 150 female participants aged 20-45 will be randomly assigned to one of three groups: a placebo, the probiotic treatment, or the pomegranate extract, for a duration of 8 weeks. The study will monitor changes in vaginal flora and inflammation through various assessments at specified intervals. Participants will also provide information on their dietary habits and health conditions throughout the trial.
Why it matters
Potential benefit: If successful, this study could lead to improved treatments for bacterial vaginitis and enhanced vaginal health in women.
How similar studies have gone: Previous studies have shown promise in using probiotics for vaginal health, suggesting that this approach may be effective.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: 1. Females aged 20-45 2. Nugent score ≥ 4 3. Menstrual cycle of 28-60 days Exclusion Criteria: 1. Pregnant or lactating women 2. Antibiotic usage 3. Other reproductive-related inflammatory diseases (e.g., candidiasis, gonorrhea, chlamydia infection) 4. Allergy to probiotics or White Pomegranate-related components
Where it's running
-
Chung Shan Medical University Hospital
Taichung, Taiwan Recruiting
Study contacts
- Study coordinator: Shih-Chien Huang
- Email: schuang@csmu.edu.tw
- Phone: +886424730022
Similar studies
Other studies for the same condition or treatment. Recruiting studies are listed first.
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Single-dose secnidazole versus multi-dose metronidazole for treating Trichomonas vaginalis
This compares a single-dose secnidazole pill with multi-dose metronidazole to see if secnidazole works better and costs less for treating Trichomonas in adults.
How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.