Effects of Intermittent Fasting and Mediterranean Diet on Multiple Sclerosis
Determination of the Effects of Intermittent Fasting and Mediterranean Diet on Quality of Life, Circadian Rhythm and Appetite Markers in Patient With Multiple Sclerosis
This study is testing whether intermittent fasting or a Mediterranean diet can improve health and quality of life for women with Multiple Sclerosis.
Quick facts
| Phase | Not applicable |
|---|---|
| Study type | Interventional |
| Enrollment | 34 (estimated) |
| Ages | 18 Years to 65 Years |
| Sex | Female |
| Sponsor | Nigde Omer Halisdemir University Academic / other |
| Locations | 1 site (Niğde, Bor) |
| Trial ID | NCT06546033 on ClinicalTrials.gov |
What this trial studies
This study investigates the impact of intermittent fasting and the Mediterranean diet on various health parameters in patients with Multiple Sclerosis (MS). It aims to evaluate how these dietary approaches affect quality of life, sleep patterns, circadian rhythms, and levels of appetite hormones such as leptin and ghrelin. The study will compare the two diets to determine which may offer greater benefits for MS patients. Participants will be women aged 18-65 diagnosed with MS, who meet specific health criteria.
Who should consider this trial
Good fit: Ideal candidates for this study are women aged 18-65 diagnosed with Multiple Sclerosis who are not currently experiencing an MS attack.
Not a fit: Patients with other autoimmune diseases, severe physical disabilities, or those who have recently undergone significant weight changes may not benefit from this study.
Why it matters
Potential benefit: If successful, this study could improve the quality of life and overall health outcomes for patients with Multiple Sclerosis through dietary interventions.
How similar studies have performed: While there is limited research directly comparing these dietary approaches in MS patients, the potential benefits of diet on chronic conditions have been explored in other studies, suggesting a promising area of investigation.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * To apply to the neurology outpatient clinic, to be a female between the ages of 18-65 who has been diagnosed with MS by a physician * Not being in the attack period * Not being in menopause Not being diagnosed with any autoimmune system disease other than -MS that may adversely affect the study, * Not following the Mediterranean diet and intermittent fasting programmes in the last three months, * Not being diagnosed with an eating behaviour disorder, * Not having any communication problems, * Signing the informed consent form, * Brain MRI within the last three months, * Not to be pregnant and lactating * No physical disability No history of cancer * Body Mass Index between 18,5 kg/m2- 29,9 kg/m2, * Not losing 5% and/or more body weight in the last month Exclusion Criteria: * Having a diagnosis of autoimmune system disease that may adversely affect working outside of -MS, * To be in the attack period-Being under 18 years of age and over 65 years of age * Being in menopause-Mediterranean diet and intermittent fasting feeding programmes within the last three months, * Diet therapy that has an effect on the autoimmune system within the last three months, * Being diagnosed with eating behaviour disorder, * Having any communication problems,- Not signing the informed consent form, * Failure to adapt to the work during the working period, to be in a situation/behaviour that may adversely affect the work, * To have applied any nutritional intervention during the last three months prior to the study, * Taking supplements such as selenium, zinc, iron, vitamin D and/or B12, which may affect the course of the study, * To have received cancer treatment and / or to be receiving cancer treatment, * Other neurological diseases (e.g. Parkinson's, epilepsy, Alzheimer's), * Diagnosed with a disease lasting more than 4 months in the last 12 months and other specialised dietary / compositionally different dietary patterns (e.g. high protein, ketogenic, low energy content \< 1000 kcal/day), * Body Mass Index \<18.5 kg/m2 or \>30 kg/m2 * Losing 5% and/or more body weight in the last month, * Having a physical disability
Where this trial is running
Niğde, Bor
- Nigde Omer Halisdemir University — Niğde, Bor, Turkey (Türkiye) (Recruiting)
Study contacts
- Study coordinator: Elif Gökçe İnbaşı, MSc.
- Email: einbasi@ohu.edu.tr
- Phone: 0388 311 86 00
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.