Effects of intermittent fasting and exercise on inflammation and metabolism in metabolic syndrome

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This intervention assesses how intermittent fasting, both alone and combined with high-intensity interval training, impacts inflammation and metabolism in individuals with obesity and metabolic syndrome. Participants will engage in a 3-month fasting regimen, with one group also participating in high-intensity interval training twice a week. The study includes control groups of individuals with metabolic syndrome and healthy individuals, and it features multiple in-house visits for assessments and nutritional counseling over a total of 6 months.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* Written consent to participate in the study.
* Persons aged 18 years and older.
* Diagnosis of Metabolic Syndrome (MetS) with elevated hsCRP.

Exclusion Criteria:

* Pregnant or nursing individuals.
* Cardiovascular diseases or orthopedic restrictions that prevent exercise.
* Use of medication or supplements that significantly affect study outcomes (e.g., anti-inflammatory medications, antibiotics within the last 6 weeks).
* Body weight greater than 200 kg (maximum capacity of training equipment).
* Individuals with mental illnesses that may impair their ability to understand or participate in the study.

Where it's running

• Hector-Center for Nutrition, Exercise and Sports, University Hospital Erlangen
  Erlangen, Bavaria, Germany Recruiting

Study contacts

• Study coordinator: Prof. Dr. med. Yurdagül Zopf
• Email: yurdaguel.zopf@uk-erlangen.de
• Phone: 0049091318545220

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.