Effects of hop compounds on the immune system
Effect of Iso-alpha Acids and Xanthohumol on the Human Immune System
This study tests whether hop compounds can affect the immune system in healthy people over a six-hour period.
Quick facts
| Phase | Not applicable |
|---|---|
| Study type | Interventional |
| Enrollment | 14 (estimated) |
| Ages | 18 Years to 70 Years |
| Sex | All |
| Sponsor | University of Vienna Academic / other |
| Locations | 1 site (Vienna) |
| Trial ID | NCT06286644 on ClinicalTrials.gov |
What this trial studies
This study investigates how Iso-alpha-Acids and Xanthohumol, compounds derived from hops, influence the immune response in healthy participants over a six-hour period. It employs a placebo-controlled crossover design where participants receive either a placebo, Xanthohumol, Iso-alpha Acids, or a combination of both, followed by blood draws at various intervals. The study aims to measure clinical parameters, blood lipids, glucose levels, uric acid, and inflammatory markers to assess the compounds' effects on the immune system.
Who should consider this trial
Good fit: Ideal candidates for this study are healthy adults with a BMI between 18.5 and 30 kg/m².
Not a fit: Patients with food intolerances, chronic inflammatory diseases, or those on immunosuppressive medication may not benefit from this study.
Why it matters
Potential benefit: If successful, this study could provide insights into natural compounds that may enhance immune function.
How similar studies have performed: While the specific combination of hop compounds is novel, similar studies on dietary compounds affecting immune response have shown promising results.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * healthy * BMI: \>18,5 kg/m² or \<30 kg/m² Exclusion Criteria: * food intolerances * food allergies * chronic inflammatory diseases * metabolic diseases * viral or bacterial infections within the last 3 weeks of inclusion * intake of immunosuppressive medication
Where this trial is running
Vienna
- University of Vienna — Vienna, Austria (Recruiting)
Study contacts
- Study coordinator: Ina Bergheim, Prof. Dr.
- Email: ina.bergheim@univie.ac.at
- Phone: +43-1-4277-54981
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.