Effects of hop compounds on the immune system

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This study investigates how Iso-alpha-Acids and Xanthohumol, compounds derived from hops, influence the immune response in healthy participants over a six-hour period. It employs a placebo-controlled crossover design where participants receive either a placebo, Xanthohumol, Iso-alpha Acids, or a combination of both, followed by blood draws at various intervals. The study aims to measure clinical parameters, blood lipids, glucose levels, uric acid, and inflammatory markers to assess the compounds' effects on the immune system.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* healthy
* BMI: \>18,5 kg/m² or \<30 kg/m²

Exclusion Criteria:

* food intolerances
* food allergies
* chronic inflammatory diseases
* metabolic diseases
* viral or bacterial infections within the last 3 weeks of inclusion
* intake of immunosuppressive medication

Where it's running

• University of Vienna
  Vienna, Austria Recruiting

Study contacts

• Study coordinator: Ina Bergheim, Prof. Dr.
• Email: ina.bergheim@univie.ac.at
• Phone: +43-1-4277-54981

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

• Velocity-based resistance training to reduce inflammation in older adults

  This program will test whether different amounts of velocity-based resistance training can lower inflammation in adults aged 60–75 who do not regularly do resistance exercise.

  Recruiting National Taipei University · Taipei · NCT07566832

• Effects of hop compounds on the immune system in overweight individuals

  This study tests whether compounds from hops can help boost the immune system in overweight people who might be at risk for metabolic diseases.

  Recruiting University of Vienna · Vienna · NCT06745102

• Exploring the effects of Daoist standing meditation on well-being

  This study is testing whether practicing Daoist standing meditation can improve well-being and reduce stress compared to doing a simple wall squat.

  Recruiting University of North Carolina, Charlotte · Charlotte, North Carolina · NCT06573034

• How exercise affects the brain and inflammation in depression

  This project tests whether adding a structured exercise program to standard antidepressant treatment helps people with moderate major depressive disorder and whether it reduces inflammation and changes brain markers.

  Recruiting at 5 sites Fundación de Investigación Biomédica - Hospital Universitario de La Princesa · Alcalá de Henares, Madrid and 4 other locations · NCT06450704

• Monitoring severe COVID-19 infections in children in Israel and England

  This study is trying to track how severe COVID-19 affects children under 16 in emergency departments in Israel and the UK to better understand the illness and its complications.

  Recruiting at 6 sites Hadassah Medical Organization · Afula and 5 other locations · NCT06434701

• Influenza vaccination's effect on heart inflammation after a heart attack

  This study is testing if getting a flu shot after a heart attack can help reduce inflammation in the heart for patients who have just had a procedure to open blocked arteries.

  Recruiting at 3 sites Phase 4 Region Örebro County · Aarhus and 2 other locations · NCT06336317

How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.