Effects of HIIT vs Strength Training on Health in Postmenopausal Women with Breast Cancer

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

The POWER Health study is a randomized clinical trial designed to evaluate metabolic flexibility and autonomic function in postmenopausal women with a history of breast cancer compared to untreated controls. Participants will undergo two different 8-week supervised exercise interventions: high-intensity interval training (HIIT) aimed at improving metabolic power and strength training focused on enhancing muscle power. The study aims to determine the impact of these interventions on cardiovascular health and overall well-being in this population. By comparing these two approaches, the trial seeks to identify the most effective exercise regimen for improving health outcomes in postmenopausal oncological women.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* Patients diagnosed of relapse free-cancer (RFC) or patients not diagnosed of any cancer at least the last 15 years (CG)
* Aged between 35 and 75 years
* Diagnostic of breast cancer (i.e., including ductal carcinoma, invasive carcinoma, triple negative; RFC) or physiological menopause (CG)
* Not participating in a nutritional/dietary intervention
* Not being physically active (i.e., not to be participating in any physical exercise program in the last 3 months, or performing less than 600 metabolic equivalents (METS)/week of moderate-vigorous physical activity).
* To be capable and willing to provide informed consent
* Not to suffer from any specific condition that may impede testing of the study hypothesis or make it unsafe to engage in the exercise intervention (i.e., determined by the research staff).

Exclusion Criteria:

* Medical contraindication for being engaged in an exercise.
* Additional surgery planned within the intervention
* Consuming usually betablocker or any drugs alterning nervous system functioning
* History of another primary invasive cancer (RFC) or suffer a serious chronic illness (CG)
* To present any of the following cardiac conditions: (i) myocardial infarction or coronary revascularization procedure within prior 3 months, (ii) uncontrolled hypertension (i.e., systolic ≥180 mmHg or diastolic ≥100 mmHg), (iii) uncontrolled arrhythmias (iv) valvular disease clinically significant, (v) decompensated heart failure or (vi) to suffer from known aortic aneurysm.

Where it's running

• Faculty of Physical Activity and Sport Sciences
  Valencia, Valencia, Spain Recruiting

Study contacts

• Principal investigator: Cristina Blasco Lafarga, Tenured Professor — University of Valencia
• Study coordinator: Cristina Blasco Lafarga, Tenured Professor
• Email: m.cristina.blasco@uv.es
• Phone: 64372

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.