Effects of gamma light stimulation on brain activity in older adults

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This study evaluates how non-flickering gamma light stimulation affects resting-state EEG rhythms and cognitive function in cognitively healthy older adults aged 55 and above. It aims to address limitations of previous studies by conducting a randomized, placebo-controlled, double-blind trial with 52 participants. The intervention involves daily light stimulation for four weeks, with assessments of brainwave activity and cognitive performance at multiple time points. The goal is to explore gamma light stimulation as a potential non-pharmacological intervention for cognitive decline.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* 1\. Age over 55 years old.
* 2\. The Cognitive Abilities Screening Instrument (CASI) score is within normal ranges adjusted for age and education.
* 3\. Participants have no history of severe neurological or psychiatric disorders (such as stroke, epilepsy, depression, migraine, etc.) that could affect cognitive function.
* 4\. Participants have not used drugs that may affect cognitive function (e.g., benzodiazepines, anticholinergic medications, etc.).
* 5\. Participants with normal or corrected vision (e.g., glasses or contact lenses) to normal levels.
* 6\. Voluntary to sign the Informed Consent Form.

Exclusion Criteria:

* 1\. Participants enrolled in any cognitive enhancement study within the past two months.
* 2\. Participants with a history of disease that could affect cognitive function (e.g., cancer, autoimmune diseases, etc.).
* 3\. Pregnant, or planning to become pregnant.

Where it's running

• Chang Gung University
  Taoyuan, Guishan, Taiwan Recruiting

Study contacts

• Study coordinator: Chia-Hsiung Cheng, Ph.D.
• Email: ch.cheng@mail.cgu.edu.tw
• Phone: +886-3-211800

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.