Clinical trial No longer in our active list Interventional Ages 18 to 65 Women only

Effects of exercise training on lipedema in women

Official title: The Effects of Endurance Training in Women With Lipedema

Run by Norwegian University of Science and Technology · NCT05488977 · Data updated 2026-05-14

This study is no longer in our active list. It may have stopped recruiting or finished. The details below are as of 2026-05-14 and are kept for reference. Check ClinicalTrials.gov for its current status, or see similar studies below.

This study is testing if an 8-week high-intensity exercise program can help women with lipedema feel better and manage their symptoms.

Quick facts

Study typeInterventional
Ages18 Years to 65 Years
SexWomen only
Enrollment40 (estimated)
SponsorNorwegian University of Science and Technology
Academic / other
Locations1 site (Trondheim)
Trial IDNCT05488977 on ClinicalTrials.gov

Is this trial a fit for you?

Likely a good fit

Ideal candidates for this study are women aged 18-65 who have been diagnosed with lipedema and can participate in supervised exercise training.

Probably not a fit

Patients with ongoing eating disorders or orthopedic limitations that prevent them from engaging in exercise training may not benefit from this study.

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This study investigates the impact of an 8-week high-intensity interval training (HIIT) program on women diagnosed with lipedema, a condition characterized by painful fat accumulation in the limbs. Thirty participants aged 18-65 will be randomly assigned to either the exercise group or a control group. The exercise regimen consists of supervised sessions twice a week, focusing on intervals that elevate heart rates significantly. Data will be collected on participants' lipedema characteristics and their use of clinical aids throughout the study.

Why it matters

Potential benefit: If successful, this study could provide a new, effective exercise-based intervention for managing lipedema symptoms and improving quality of life for affected women.

How similar studies have gone: While few studies have explored exercise training for lipedema, existing guidelines suggest that physical activity is beneficial, indicating potential for success in this approach.

Who can join: the full rules

Show full inclusion / exclusion criteria
Inclusion Criteria:

- can meet for supervised exercise training in Trondheim.

Exclusion Criteria:

* eating disorders and/or orthopedic limitations for exercise training

Where it's running

  • Institute for Circulation and Medical Imaging, NTNU
    Trondheim, Norway
    Recruiting

Study contacts

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

  • Kinesio Taping Added to Standard Care for Women with Lipedema

    This study tests whether adding kinesio taping to usual care helps reduce pain for women with stage II lipedema.

    Recruiting Kanuni Sultan Suleyman Training and Research Hospital · Küçükçekmece, Istanbul · NCT07919574

  • Comparison of body composition in lipedema and obesity

    This study tests whether women with lipedema have different segmental body fat and muscle distribution compared with BMI-matched women without lipedema.

    Recruiting Sultan Abdulhamid Han Training and Research Hospital, Istanbul, Turkey · Istanbul, Uskudar · NCT07878299

  • Comparison of Different Exercise Protocols for Lipedema

    This study tests whether high‑intensity interval training or moderate‑intensity continuous training improves function, strength, and quality of life in adults with lipedema.

    Recruiting Hitit University · Çorum · NCT07873541

  • taVNS-enriched rehab for lipedema

    This study tests whether adding transcutaneous auricular vagus nerve stimulation (taVNS) to standard rehabilitation helps people with lipedema reduce symptoms.

    Recruiting Istanbul University - Cerrahpasa · Istanbul, Eyupsultan · NCT07857499

  • Manual and self-lymphatic drainage with exercise for lipedema

    This study tests whether manual lymph drainage plus supervised exercise works better than self-lymph drainage plus guided activity for reducing pain and improving function in women with lipedema over six weeks.

    Recruiting Istanbul University - Cerrahpasa · Istanbul, Eyupsultan · NCT07803926

  • Turkish version of the Duke Activity Status Index in women with lipedema

    This study tests whether the Turkish Duke Activity Status Index accurately and consistently measures functional capacity in women with lipedema.

    Recruiting Istanbul University - Cerrahpasa · Istanbul, Eyupsultan · NCT07803913

How to take part

  1. Review the eligibility criteria above with your treating physician.
  2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
  3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.