Effects of exercise training in lymphoma survivors

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This study compares the effects of aerobic exercise with or without resistance exercise to usual care in individuals treated with anthracyclines for lymphoma. It includes a randomized controlled trial with lymphoma survivors and a reference group of age- and sex-matched individuals without a history of cancer. The primary endpoint is the change in cardiorespiratory fitness, assessed as VO2peak, while secondary endpoints include cardiovascular risk factors and patient-reported outcomes. Participants will be recruited through invitation only.

Why it matters

Who can join: the full rules

Inclusion Criteria Lymphoma participants:

* Listed in relevant registers
* Confirmed lymphoma diagnosis (i.e., Hodgkin lymphoma and aggressive non-Hodgkin lymphoma)
* Completed treatment in the past two to five years without relapse or second cancer
* Previous anthracycline treatment with or without mediastinal radiation
* No severe cancer-related fatigue (per self-report)

Inclusion Criteria Lymphoma participants and non-cancer reference group:

* Currently not performing \>75 minutes/week of aerobic exercise
* Willing and able to adhere to all study procedures.

Exclusion Criteria Lymphoma participants:

* Relapse since diagnosis
* A history, or current presence, of another diagnosis of invasive cancer of any kind

Exclusion Criteria Lymphoma participants and non-cancer reference group:

* Presence of any uncontrolled- or recent cardiovascular disease
* Has undergone heart surgery
* Uses a pacemaker
* Pregnancy
* Unable to read and understand Swedish (applicable for the Swedish site only)
* Unable to read and understand Norwegian (applicable for the Norwegian site)
* Any physical or mental health condition restricting adherence to study protocol

Where it's running

• Helena Igelström
  Uppsala, Sweden Recruiting
• Norweigan School of Sport Sciences
  Oslo, Norway Not yet recruiting

Study contacts

• Principal investigator: Tormod S. Nilsen, PhD — Norwegian School of Sport Sciences
• Study coordinator: Tormod S. Nilsen, PhD
• Email: tormodsn@nih.no
• Phone: 95069857

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.