Effects of exercise in low oxygen conditions on health markers in young men

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This study investigates how a 4-week exercise program conducted under normobaric hypoxia affects inflammatory markers, oxidative stress levels, intestinal damage, and mitochondrial metabolism in young sedentary males. Participants will undergo a proprietary training regimen designed to enhance oxygen transport and improve the body's antioxidant capacity and gut health. The study aims to develop practical training guidelines for coaches and athletes based on the findings. A medical examination will ensure participants meet health criteria before joining the program.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* no known metabolic diseases, no contraindications to physical exercise and no history of high altitude sickness stated in interview. A medical examination (including ECG, blood and urine tests) is required.

Exclusion Criteria:

* changes in diet during the experiment, smoking and abuse of alcohol and/or other stimulants.

Where it's running

• University School of Physical Education in Cracow
  Krakow, Poland Recruiting

Study contacts

• Study coordinator: Anna Radoń, MSc
• Email: anna.radon@awf.krakow.pl
• Phone: +45126831142

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

• Heat and hypoxia: how simulated altitude affects body temperature and strain

  This study tests how heat exposure with and without simulated altitude affects core temperature and physiological strain in healthy, physically active adult men.

  Recruiting University of Ottawa · Ottawa, Ontario · NCT07664462

• How acute low-oxygen levels affect the right side of the heart in asthma

  This study tests how short-term exposure to simulated high-altitude oxygen levels affects right heart function in adults with asthma.

  Recruiting University of Zurich · Zurich, Canton of Zurich · NCT07431580

• How short-term low oxygen exposure affects the right side of the heart in healthy adults

  We test whether short-term reduced oxygen (simulated 2,500 m and 4,000 m) changes right ventricular function in healthy adults at rest and during light exercise.

  Recruiting University of Zurich · Zurich, Canton of Zurich and 1 other locations · NCT07431567

• Right-heart response to short-term low oxygen in people with past HAPE

  This trial tests whether brief exposure to simulated high altitude (low oxygen) changes right-heart function in adults who previously had high-altitude pulmonary edema (HAPE).

  Recruiting University of Zurich · Zurich · NCT07431554

• How altitude affects outcomes for children with acute respiratory distress

  This project will see if higher altitude and differences in hospital critical-care resources change outcomes for children (1 month–18 years) with PARDS who need invasive mechanical ventilation.

  Recruiting at 18 sites Latin American Pediatric Collaborative Network · Sucre, Chuquisaca Department and 19 other locations · NCT07193771

• Acetazolamide and plasma volume changes at high altitude

  This study will see if acetazolamide helps prevent early plasma volume loss and related altitude symptoms in healthy adults who normally live at low altitude.

  Recruiting Phase 4 Centre d'Expertise sur l'Altitude EXALT · Bishkek · NCT07118462

How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.