Effects of exercise in low oxygen conditions on health markers in young men
The Influence of Physical Training in Normobaric Hypoxia on Prooxidant-Antioxidant Imbalance, Inflammatory Marker Levels, Intestinal Damage Degree, and Mitochondrial Energy Release Rate in Young Non-trained Males
NA · University School of Physical Education, Krakow, Poland · NCT06204731
This study tests if a special 4-week exercise program in low oxygen conditions can improve health markers like inflammation and gut health in young men who don’t usually exercise.
Quick facts
| Phase | NA |
|---|---|
| Study type | Interventional |
| Enrollment | 50 (estimated) |
| Ages | 19 Years to 29 Years |
| Sex | Male |
| Sponsor | University School of Physical Education, Krakow, Poland (other) |
| Locations | 1 site (Krakow) |
| Trial ID | NCT06204731 on ClinicalTrials.gov |
What this trial studies
This study investigates how a 4-week exercise program conducted under normobaric hypoxia affects inflammatory markers, oxidative stress levels, intestinal damage, and mitochondrial metabolism in young sedentary males. Participants will undergo a proprietary training regimen designed to enhance oxygen transport and improve the body's antioxidant capacity and gut health. The study aims to develop practical training guidelines for coaches and athletes based on the findings. A medical examination will ensure participants meet health criteria before joining the program.
Who should consider this trial
Good fit: Ideal candidates for this study are young sedentary males without metabolic diseases or contraindications to physical exercise.
Not a fit: Patients with metabolic diseases, a history of high altitude sickness, or those who smoke or abuse substances may not benefit from this study.
Why it matters
Potential benefit: If successful, this study could provide insights into improving athletic performance and overall health through specialized training in low oxygen environments.
How similar studies have performed: While the approach of training under normobaric hypoxia is gaining interest, the specific impacts on the outlined health markers in young males are less explored, making this study somewhat novel.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * no known metabolic diseases, no contraindications to physical exercise and no history of high altitude sickness stated in interview. A medical examination (including ECG, blood and urine tests) is required. Exclusion Criteria: * changes in diet during the experiment, smoking and abuse of alcohol and/or other stimulants.
Where this trial is running
Krakow
- University School of Physical Education in Cracow — Krakow, Poland (RECRUITING)
Study contacts
- Study coordinator: Anna Radoń, MSc
- Email: anna.radon@awf.krakow.pl
- Phone: +45126831142
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.
Conditions: Hypoxia, Altitude, inflammation, oxidative stress, intestinal damage, muscle damage, mitochondrial metabolism, normobaric hypoxia, training