Effects of education and exercise on hip osteoarthritis outcomes
Effects of EDUcation and EXercise Compared to Education Alone on Clinical and Physiological Outcomes in Patients With Hip Osteoarthritis
This study is testing if combining exercise with education can help people with hip osteoarthritis feel better and improve their joint health.
Quick facts
| Phase | Not applicable |
|---|---|
| Study type | Interventional |
| Enrollment | 150 (estimated) |
| Ages | 45 Years and up |
| Sex | All |
| Sponsor | University of Aarhus Academic / other |
| Locations | 2 sites (Aarhus C and 1 other locations) |
| Trial ID | NCT06391554 on ClinicalTrials.gov |
What this trial studies
The EduEx trial aims to evaluate whether adding progressive resistance training (PRT) to a patient education program (EDU) can enhance clinical outcomes for individuals with hip osteoarthritis. This multicenter, randomized controlled trial will recruit 150 participants who will be assigned to either the PRT+EDU group or the EDU alone group. The study will include both clinical evaluations and a mechanistic assessment involving MRI scans to explore the effects of exercise on hip joint structures. Follow-up assessments will occur at 3 months and 12 months to measure outcomes.
Who should consider this trial
Good fit: Ideal candidates are individuals aged 45 and older with clinically diagnosed hip osteoarthritis and daily hip pain.
Not a fit: Patients scheduled for total hip replacement within the next 12 months or those with significant comorbidities affecting hip function may not benefit from this study.
Why it matters
Potential benefit: If successful, this study could lead to improved pain management and functional outcomes for patients with hip osteoarthritis.
How similar studies have performed: Previous studies have shown positive outcomes with exercise interventions for osteoarthritis, suggesting potential success for this approach.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * Clinically diagnosed with hip OA according to the criteria by the National Institute for Health and Care Excellence (NICE) * Radiographic verification of hip OA diagnosis with Kellgren Lawrence score of 2 or 3 in one or both hips * Not scheduled for a total hip replacement within the following 12 months * An event of hip pain every day of at least 3 out of 10 on a numerical rating scale during the last 14 days * Age ≥ 45 years * Adequacy in written and spoken Danish Exclusion Criteria: * Comorbidity that markedly influences hip function or degeneration of tissue in or around the hip joint (rheumatic, neurological, mental or other) * Surgery in the lower extremities within the six months prior to inclusion * BMI \> 40 * Pregnancy * Resistance exercise (weights or elastic bands) for the lower extremities exceeding 12 sessions over the last 6 months or 6 sessions over the last 3 months * Suffering from claustrophobia or not tolerating whole body MRI scanner * Metallic implants from the waist to just above the knee * Pacemaker or other medical devices that are not MR approved
Where this trial is running
Aarhus C and 1 other locations
- Aarhus University — Aarhus C, Denmark (Not_yet_recruiting)
- Aarhus University Hospital — Aarhus N, Denmark (Recruiting)
Study contacts
- Principal investigator: Troels Kjeldsen, MSc — Aarhus University Hospital
- Study coordinator: Troels Kjeldsen, MSc
- Email: tkjeldsen@clin.au.dk
- Phone: 4560137627
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.