Effects of education and exercise on hip osteoarthritis outcomes

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

The EduEx trial aims to evaluate whether adding progressive resistance training (PRT) to a patient education program (EDU) can enhance clinical outcomes for individuals with hip osteoarthritis. This multicenter, randomized controlled trial will recruit 150 participants who will be assigned to either the PRT+EDU group or the EDU alone group. The study will include both clinical evaluations and a mechanistic assessment involving MRI scans to explore the effects of exercise on hip joint structures. Follow-up assessments will occur at 3 months and 12 months to measure outcomes.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* Clinically diagnosed with hip OA according to the criteria by the National Institute for Health and Care Excellence (NICE)
* Radiographic verification of hip OA diagnosis with Kellgren Lawrence score of 2 or 3 in one or both hips
* Not scheduled for a total hip replacement within the following 12 months
* An event of hip pain every day of at least 3 out of 10 on a numerical rating scale during the last 14 days
* Age ≥ 45 years
* Adequacy in written and spoken Danish

Exclusion Criteria:

* Comorbidity that markedly influences hip function or degeneration of tissue in or around the hip joint (rheumatic, neurological, mental or other)
* Surgery in the lower extremities within the six months prior to inclusion
* BMI \> 40
* Pregnancy
* Resistance exercise (weights or elastic bands) for the lower extremities exceeding 12 sessions over the last 6 months or 6 sessions over the last 3 months
* Suffering from claustrophobia or not tolerating whole body MRI scanner
* Metallic implants from the waist to just above the knee
* Pacemaker or other medical devices that are not MR approved

Where it's running

• Aarhus University Hospital
  Aarhus N, Denmark Recruiting
• Aarhus University
  Aarhus C, Denmark Not yet recruiting

Study contacts

• Principal investigator: Troels Kjeldsen, MSc — Aarhus University Hospital
• Study coordinator: Troels Kjeldsen, MSc
• Email: tkjeldsen@clin.au.dk
• Phone: 4560137627

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.