Effects of eating sourdough bread on energy intake and appetite
Impact of Sourdough Bread Consumption on Long-term Energy Intake: A Pilot Study of Feasibility (SOBER)
This study is testing if eating sourdough bread regularly can help people manage their appetite and weight over four weeks.
Quick facts
| Phase | Not applicable |
|---|---|
| Study type | Interventional |
| Enrollment | 100 (estimated) |
| Ages | 18 Years to 50 Years |
| Sex | All |
| Sponsor | KU Leuven Academic / other |
| Locations | 1 site (Leuven, Vlaams Brabant) |
| Trial ID | NCT05590611 on ClinicalTrials.gov |
What this trial studies
This pilot study investigates the impact of long-term sourdough bread consumption on energy intake and blood lipid levels over a four-week period. Participants, both normal-weight and overweight, will consume sourdough bread as part of their regular diet to assess changes in appetite regulation and body weight. The study aims to determine the feasibility of this dietary intervention and its potential effects on eating behavior. Participants will be monitored for their dietary habits and any changes in their health metrics.
Who should consider this trial
Good fit: Ideal candidates are adults aged 18-50 with a BMI over 20 who regularly consume brown bread.
Not a fit: Patients with gastrointestinal disorders, gluten sensitivity, or those who already consume sourdough bread may not benefit from this study.
Why it matters
Potential benefit: If successful, this study could provide insights into dietary strategies for managing appetite and body weight.
How similar studies have performed: While this approach is relatively novel, similar dietary interventions have shown promise in managing energy intake and weight.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * Female and male participants * Age range 18 - 50 * BMI range \>20 kg/m2 at screening visit * Regular eating pattern (3 meals per day on at least 5 days per week) * Habitual brown bread consumption of at least 1 slice per day (assessed by The European Prospective Investigation into Cancer (EPIC) Norfolk FFQ) * Stable body weight for the last 6 months Exclusion Criteria: * Currently smoking or willingness to smoke during the study period * Pregnancy, lactation or wish to become pregnant during the study period * Previous or current gastrointestinal or endocrine disorders * Previous or current substance/alcohol dependence or abuse (\> 2 units per day/14 units per week) * Coeliac disease or gluten sensitivity * Allergy/intolerance to milk, egg, nuts, soy or sesame * Habitual sourdough bread consumption of at least 1 slice per day (assessed by The European Prospective Investigation into Cancer (EPIC) Norfolk FFQ) * Excessive concern about eating habits or body weight as evidenced from scores \< 18 on the restraint and disinhibition subscales of the Three-Factor Eating Questionnaire (Stunkard \& Messick, 1985)
Where this trial is running
Leuven, Vlaams Brabant
- KU Leuven — Leuven, Vlaams Brabant, Belgium (Recruiting)
Study contacts
- Principal investigator: Kristin Verbeke — KU Leuven
- Study coordinator: Georgia Chatonidi
- Email: georgia.chatonidi@kuleuven.be
- Phone: +3216194324
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.