Effects of Different Resistance Training on Quality of Life in Women with Hypothyroidism

Nonlinear Versus Linear Periodized Resistance Training on Quality of Life in Females With Hypothyroidism

NA · Cairo University · NCT06757712

This study is testing whether different types of strength training can improve the quality of life for women aged 35 to 45 who have hypothyroidism.

Quick facts

PhaseNA
Study typeInterventional
Enrollment75 (estimated)
Ages35 Years to 45 Years
SexFemale
SponsorCairo University (other)
Locations1 site (Suez)
Trial IDNCT06757712 on ClinicalTrials.gov

What this trial studies

This study aims to compare the effects of nonlinear and linear periodized resistance training on the quality of life in females diagnosed with hypothyroidism. Given the increasing prevalence of thyroid dysfunction, particularly among women, the study seeks to explore how structured exercise regimens can enhance physical fitness and overall well-being. Participants will engage in either nonlinear or linear periodized training, alongside their standard medical treatment, to assess improvements in their quality of life. The study will focus on women aged 35 to 45 with controlled hypothyroidism and specific body mass index criteria.

Who should consider this trial

Good fit: Ideal candidates for this study are females aged 35 to 45 with controlled hypothyroidism and a body mass index between 30 and 34.9 kg/m2.

Not a fit: Patients with uncontrolled coronary or cerebrovascular disease, cognitive impairments, or those who have recently undergone musculoskeletal surgery may not benefit from this study.

Why it matters

Potential benefit: If successful, this study could lead to improved quality of life for women with hypothyroidism through tailored exercise interventions.

How similar studies have performed: While exercise has been shown to improve quality of life in various chronic conditions, the specific comparison of nonlinear versus linear periodization in hypothyroid patients is a novel approach.

Eligibility criteria

Show full inclusion / exclusion criteria
Inclusion Criteria:

* Be controlled hypothyroidism (TSH level within 0.5 - 4.5 mU/L)
* Be ranged from 35 to 45 years
* Female patients
* Body Mass Index 30-34.9 kg/m2 .
* triglyceride-glucose (TyG) index \> 4.5

Exclusion Criteria:

* history of pulmonary disease
* Patients with uncontrolled coronary or cerebrovascular disease
* Those who underwent musculoskeletal surgery within the previous year
* Recent history of lower and upper limb fracture , hip and shoulder dislocation.
* Cognitive impaired patients
* Patients with history of epilepsy
* Patients who participating in any other exercise program

Where this trial is running

Suez

Study contacts

How to participate

  1. Review the eligibility criteria above with your treating physician.
  2. Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
  3. Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.

View on ClinicalTrials.gov →

Conditions: Hypothyroidism

Last reviewed 2026-05-15 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.