Effects of different physiotherapy approaches on neck pain and related outcomes in chronic non-specific neck pain

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This randomized, single-blind trial compares three intervention arms in adults 18–65 with chronic non-specific neck pain. Participants are randomized to structured exercise, sensorimotor training, or pain neuroscience education, delivered over several weeks at Istanbul Medipol University. Outcomes include disability, pain intensity, sensorimotor control, and psychosocial factors, within a biopsychosocial framework. Stratification by Central Sensitization Inventory scores ensures balanced groups. Assessors and statisticians are blinded to allocation to minimize bias.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* Diagnosis of chronic non-specific neck pain lasting for more than 90 days
* Age between 18 and 65 years (inclusive)
* History of receiving standard physical therapy in a clinical setting in Turkey, yet experiencing persistent neck pain
* Numeric Pain Rating Scale (NPRS) score ≥ 3/10 at rest and during active cervical movement
* Neck Disability Index (NDI) score ≥ 5/50
* Voluntary agreement to participate and signing of the informed consent form

Exclusion Criteria:

* Neck pain associated with nerve root involvement or radiculopathy
* History of prior cervical spine surgery
* Physical therapy interventions received within the last 3 months
* Severe spinal pathologies (e.g., fracture, tumor, infection, structural instability)
* Systemic conditions (e.g., rheumatic, neurological, metabolic diseases)
* Presence of vertigo or sensory loss
* History of cancer within the last 5 years

Where it's running

• Istanbul Medipol University
  Istanbul, Beykoz, Turkey (Türkiye) Recruiting

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Other studies for the same condition or treatment. Recruiting studies are listed first.

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.