Effects of different exercise intensities on health measures
The Impact of 6 Weeks of Moderate- and Heavy-intensity Continous Training on Peak Oxygen Uptake, Plasma Extracellular Vesicles and Inflammatory Cytokines
NA · University of British Columbia · NCT06398548
This study is testing how different levels of indoor cycling intensity can improve fitness and health in healthy young adults over six weeks.
Quick facts
| Phase | NA |
|---|---|
| Study type | Interventional |
| Enrollment | 50 (estimated) |
| Ages | 18 Years to 40 Years |
| Sex | All |
| Sponsor | University of British Columbia (other) |
| Locations | 1 site (Kelowna, British Columbia) |
| Trial ID | NCT06398548 on ClinicalTrials.gov |
What this trial studies
This study investigates how varying intensities of indoor cycling affect fitness and health markers in healthy young adults. Participants will undergo a maximal cycling test to assess their fitness levels before and after a 6-week training program. They will be divided into three groups: one cycling at a moderate pace, another at a slightly harder pace, and a control group maintaining their usual activities. Blood samples will be collected to analyze physiological markers related to inflammation, metabolism, and extracellular vesicles. The study aims to provide insights into the optimal exercise intensity for health benefits.
Who should consider this trial
Good fit: Ideal candidates for this study are healthy young adults aged 18 to 40 with a normal body mass index and no history of metabolic or cardiovascular diseases.
Not a fit: Patients with metabolic conditions, cardiovascular diseases, or those who are elite athletes may not benefit from this study.
Why it matters
Potential benefit: If successful, this study could help identify the most effective exercise intensity for improving overall health and fitness in young adults.
How similar studies have performed: Other studies have shown promising results with varying exercise intensities, making this approach both relevant and potentially impactful.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * Are between the ages of 18 and 40 years old. * Have a body mass index (BMI) between 18.5 and 30 kg/m\^2. * Perform between 60 and 200 minutes of aerobic physical activity per week. * Do not have a history of cardiovascular disease or diabetes. Exclusion Criteria: * Require immunomodulatory medication to treat an auto-immune disease, or rely heavily on over the counter anti-inflammatory medications (e.g., Advil). * Have a metabolic condition such as diabetes. * Have hypertension (blood pressure \> 160/90 mmHg). * Are uncomfortable with blood sampling. * Are an elite endurance athlete, or training specifically for an endurance event (\>3 structured aerobic training sessions, or \>150 min of specific aerobic-based/endurance training per week). * Adhere to an extreme diet (e.g., ketogenic diet, time restricted feeding). * Smoke cigarettes
Where this trial is running
Kelowna, British Columbia
- ART 115 — Kelowna, British Columbia, Canada (RECRUITING)
Study contacts
- Study coordinator: Jonathan P Little, PhD
- Email: jonathan.little@ubc.ca
- Phone: 2508079876
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.
Conditions: Exercise Training, Lactate Threshold, Exercise Intensity Domain, VO2peak, Extracellular Vesicles, Mitochondrial Respiration