Effects of different blood flow restriction methods on bicep curls
Acute Effects of Autoregulated and Non-autoregulated Blood Flow Restrictive Bicep Curls on Indices of Arterial Stiffness and Muscle Morphology
This study is testing how two different methods of restricting blood flow during bicep curls affect the stiffness of arteries in young, active adults.
Quick facts
| Phase | Not applicable |
|---|---|
| Study type | Interventional |
| Enrollment | 20 (estimated) |
| Ages | 18 Years to 40 Years |
| Sex | All |
| Sponsor | Salisbury University Academic / other |
| Locations | 1 site (Salisbury, Maryland) |
| Trial ID | NCT05748821 on ClinicalTrials.gov |
What this trial studies
This study investigates the acute effects of autoregulated (AR) and non-autoregulated (NAR) blood flow restriction (BFR) during bicep curls on arterial stiffness. Twenty physically active adults aged 18-40 will participate in three treatment sessions, including a control session without BFR, AR BFR, and NAR BFR, conducted in a randomized order. Each session will involve a series of tests such as blood pressure measurements, ultrasonography of the carotid artery, and strength assessments. The goal is to differentiate the physiological changes induced by the two BFR methods.
Who should consider this trial
Good fit: Ideal candidates are physically active women aged 18-40 with stable weight and regular menstrual cycles.
Not a fit: Patients with cardiovascular diseases, metabolic disorders, or those who are pregnant or nursing may not benefit from this study.
Why it matters
Potential benefit: If successful, this study could provide insights into optimizing blood flow restriction techniques for improving vascular health.
How similar studies have performed: While there is ongoing research in blood flow restriction techniques, this specific comparison of autoregulated versus non-autoregulated methods is relatively novel.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: 1. Age 18-40 years old 2. Physically active (\> 6 months of consistent exercise training) 3. Weight stable for previous 6 months (+/-2.5 kg) 4. Female subjects only- reported regular menstrual cycles for the last 2 years Exclusion Criteria: 1. BP\>140/90 mmHg 2. BMI\>40 kg/m2 3. Diabetes 4. Familial hypercholesterolemia 5. Past or current history of CHD, stroke or major CVD events. Respiratory diseases (not including asthma), endocrine or metabolic, neurological, or hematological disorders that would compromise the study or the health of the subject. 6. Women must not be pregnant, plan to become pregnant during the study, or be nursing 7. Active renal or liver disease 8. All medications and supplements that influence dependent variables 9. Recent surgery \< 2 months 10. Alcohol abuse 11. Sleep apnea 12. Claustrophobia
Where this trial is running
Salisbury, Maryland
- Salisbury University — Salisbury, Maryland, United States (Recruiting)
Study contacts
- Study coordinator: Tim Werner, PhD
- Email: tjwerner@salisbury.edu
- Phone: 410-548-3526
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.