Effects of Dexmedetomidine on Anesthesia for Upper Limb Surgery
Dexmedetomidine as an Adjuvant to Local Anesthesia in Supraclavicular Plexus Block, A Randomized Control Trial.
This study is testing if adding Dexmedetomidine to Bupivacaine can improve pain relief during upper limb surgeries for patients.
Quick facts
| Phase | Not applicable |
|---|---|
| Study type | Interventional |
| Enrollment | 70 (estimated) |
| Ages | 18 Years to 75 Years |
| Sex | All |
| Sponsor | An-Najah National University Academic / other |
| Locations | 1 site (Nablus, Wes-Bank) |
| Trial ID | NCT04981951 on ClinicalTrials.gov |
What this trial studies
This study evaluates the impact of combining Dexmedetomidine with Bupivacaine for analgesia during supraclavicular brachial plexus block in patients undergoing upper limb surgeries. A total of 140 participants will be randomly assigned to receive either Bupivacaine alone or Bupivacaine with Dexmedetomidine. The onset and duration of anesthesia will be monitored using ultrasound guidance to ensure precise needle placement and safety. Participants will be assessed for sensory and motor block at regular intervals following the injection.
Who should consider this trial
Good fit: Ideal candidates are adults aged 18-75 with ASA physical status grades 1 or 2 who require upper limb surgery.
Not a fit: Patients with known hypersensitivity to the study drugs, uncontrolled diabetes, or severe coagulopathy may not benefit from this study.
Why it matters
Potential benefit: If successful, this approach could enhance pain management and improve recovery times for patients undergoing upper limb surgeries.
How similar studies have performed: Previous studies have shown promising results with similar combinations of local anesthetics and adjuncts like Dexmedetomidine, indicating potential for success.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * Aged between 18-75 years. * Classified as grades 1 or 2 by the American Society of Anesthesiology Classification of .physical status. * Willing and able to sign a consent form. Exclusion Criteria: * Patients under the following conditions will be excluded: Known hypersensitivity to Bupivacaine, Dexmedetomidine, and local anesthetics. * Uncontrolled diabetes mellitus. * Peripheral neuropathy. * SevereCoagulopathy. * Infection at the site of block. * Pregnancy. * Cardiac arrhythmias. * Prescription of beta blockers. * Psychological disorders.
Where this trial is running
Nablus, Wes-Bank
- Zaher Nazzal — Nablus, Wes-Bank, Palestinian Territory, occupied (Recruiting)
Study contacts
- Principal investigator: Zaher Nazzal, MD — An-Najah National University
- Study coordinator: Zaher Nazzal, MD
- Email: znazzal@najah.edu
- Phone: (+970) 9 2345113
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.