Effects of Depo-Medrol on Psoas Muscle After Lumbar Spine Surgery

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This study investigates the impact of administering a corticosteroid, Depo-Medrol, to the psoas muscle following a transpsoas lateral lumbar interbody fusion (LLIF) procedure. It aims to assess differences in postoperative thigh pain, hip flexor weakness, and numbness between patients receiving the injection and those who do not. The study will measure outcomes at three postoperative intervals: 2-3 weeks, 6 weeks, and 12 weeks, using various pain and quality of life scales. Additionally, it will evaluate the effect of Depo-Medrol on fusion rates and consider how patient demographics and comorbidities influence outcomes.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* Patients from the practices of Drs. Singh, Mallozzi, Moss
* Transpsoas (PTP or LTP) lateral lumbar interbody fusion (LLIF) 1-3 disc levels with posterior instrumentation (Open or MIS) with or without laminectomy, must include L3-4 and/or L4-5
* Patients who agree to be a part of the study
* Patients with lumbar disc degeneration
* Patients between ages of 18 and 75

Exclusion Criteria:

* Scoliosis \>10°
* Spondylolisthesis \>Grade 1
* Flatback deformity
* Patients with insulin dependent diabetes
* Patients with \>3 levels of fusion
* Alternative interbodies
* Chronic oral steroid users
* Patients with allergy/intolerance to depo-medrol or other steroids
* Patients requiring bilateral transpsoas approaches
* Patients with ipsilateral symptomatic hip pathology
* Revision fusion procedures
* Cases involving trauma, tumor, or infection
* Patient's not capable of providing consent themselves
* Non-fluent English speakers (for consenting reasons)
* Patients who are lost to follow-up before the two year follow up period

Where it's running

• UConn Health
  Farmington, Connecticut, United States Recruiting

Study contacts

• Principal investigator: Hardeep Singh, M.D. — UConn Health
• Study coordinator: Hardeep Singh, MD
• Email: uconnorthopaedics@uchc.edu
• Phone: 860-679-6883

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.