Effects of combined training on fatigue and quality of life in breast cancer patients
Effects of Different Volumes of Combined Training on Neuromuscular Parameters of Women in Initial Treatment for Breast Cancer: A Randomized Controlled Trial
This study is testing if different amounts of combined exercise can help women with breast cancer feel less tired and improve their quality of life during treatment.
Quick facts
| Phase | Not applicable |
|---|---|
| Study type | Interventional |
| Enrollment | 84 (estimated) |
| Ages | 18 Years and up |
| Sex | Female |
| Sponsor | Federal University of Rio Grande do Sul Academic / other |
| Drugs / interventions | chemotherapy, radiation |
| Locations | 2 sites (Pôrto Alegre and 1 other locations) |
| Trial ID | NCT03314168 on ClinicalTrials.gov |
What this trial studies
This study investigates how different volumes of combined training impact fatigue, neuromuscular function, cardiorespiratory capacity, and overall quality of life in women with breast cancer undergoing primary treatment. Participants will be divided into two groups: one receiving combined training and the other receiving physiotherapy sessions as a control. The goal is to determine the optimal dosage of resistance training needed to alleviate treatment-related side effects and improve patient outcomes. This research addresses a gap in existing literature regarding exercise prescription for breast cancer patients.
Who should consider this trial
Good fit: Ideal candidates are women diagnosed with stage I or II breast cancer who are undergoing adjuvant or neoadjuvant chemotherapy.
Not a fit: Patients with uncontrolled hypertension, heart failure, or significant skeletal muscle impairments may not benefit from this study.
Why it matters
Potential benefit: If successful, this study could lead to improved management of fatigue and enhanced quality of life for breast cancer patients during treatment.
How similar studies have performed: Previous studies have shown positive effects of combined training on breast cancer patients, but this specific investigation into varying training volumes is novel.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * Breast cancer diagnostic at I and II stages; * Adjuvant or neoadjuvant chemotherapy (≤50% of sessions completed); * More than 18 years. Exclusion Criteria: * Current smoking * Diabetic neuropathy; * Hypertension uncontrolled; * Heart failure; * Clinical depression; * Skeletal muscle impairment which not allow physical exercise.
Where this trial is running
Pôrto Alegre and 1 other locations
- Hospital Moinhos de Vento — Pôrto Alegre, Brazil (Recruiting)
- Universidade Federal do Rio Grande do Sul — Pôrto Alegre, Brazil (Recruiting)
Study contacts
- Principal investigator: Ronei Pinto, PhD — Federal University of Rio Grande do Sul
- Study coordinator: Joao Henkin, BsC
- Email: joaohenkin@gmail.com
- Phone: +5551 99302 3340
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.