Effects of cannabis use on sedation during dental procedures
Effects of Cannabis Use on Sedation Requirements for Oral Surgery Procedures
This study tests how regular cannabis use affects the effectiveness of sedation during dental extractions for patients who use cannabis often.
Quick facts
| Phase | Phase 4 |
|---|---|
| Study type | Interventional |
| Enrollment | 60 (estimated) |
| Ages | 18 Years and up |
| Sex | All |
| Sponsor | University of Oklahoma Academic / other |
| Locations | 1 site (Oklahoma City, Oklahoma) |
| Trial ID | NCT05873465 on ClinicalTrials.gov |
What this trial studies
This clinical trial investigates how chronic cannabis use affects sedation during dental extractions performed under general anesthesia. It aims to clarify the optimal sedation protocols for patients who regularly use cannabis, focusing on the administration of Midazolam, Fentanyl, and Propofol. The procedures will take place at the Oral and Maxillofacial Surgery Clinic at the College of Dentistry, ensuring a controlled environment for assessing sedation efficacy and safety.
Who should consider this trial
Good fit: Ideal candidates are adults over 18 years old who require dental extractions and have a low ASA classification.
Not a fit: Patients with a high ASA classification, significant obesity, or those taking mood-altering medications may not benefit from this study.
Why it matters
Potential benefit: If successful, this study could lead to improved sedation practices for cannabis users undergoing dental procedures, enhancing patient safety and comfort.
How similar studies have performed: While the effects of cannabis on sedation are not extensively studied, this approach is novel and aims to fill a significant gap in current medical knowledge.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * Patients older than 18 years of age * Class I or II according to the American Society of Anesthesiology (ASA) * Need for dental extractions * Extraction procedures with similar level of complexity Exclusion Criteria: * Surgical time lesser than 10 or greater than 30 minutes * ASA status of III or greater * BMI greater than 30 k/m2 * Pregnancy * Use of anti-depressants, sedatives, or other mood-altering medications * History of illicit substance abuse, alcoholism, or chronic opioid use
Where this trial is running
Oklahoma City, Oklahoma
- College of Dentistry — Oklahoma City, Oklahoma, United States (Recruiting)
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.