Effects of breaking up sitting time on children's health
Testing the Efficacy of Multi-day Interruptions in Sedentary Behaviors on Metabolic, Cognitive, and Affective Outcomes in Youth at Risk for Type 2 Diabetes
This study is testing if breaking up long periods of sitting with short activities can help overweight kids aged 8-11 improve their health and reduce the risk of type 2 diabetes.
Quick facts
| Phase | Not applicable |
|---|---|
| Study type | Interventional |
| Enrollment | 188 (estimated) |
| Ages | 8 Years to 11 Years |
| Sex | All |
| Sponsor | University of Southern California Academic / other |
| Locations | 1 site (Los Angeles, California) |
| Trial ID | NCT04469790 on ClinicalTrials.gov |
What this trial studies
This randomized controlled trial aims to evaluate the impact of multi-day interruptions in sedentary behavior compared to single bouts of exercise on various health outcomes in children aged 8-11 who are overweight or obese and at risk for type 2 diabetes. The study will utilize continuous glucose monitoring to assess metabolic responses, cognitive functions, mood, and cardiac autonomic nervous system function. By investigating these effects over multiple days, the trial seeks to provide insights into effective strategies for reducing obesity-related health risks in children. The findings could inform future interventions aimed at promoting healthier lifestyles among youth.
Who should consider this trial
Good fit: Ideal candidates for this study are children aged 8-11 years who are in good general health and have a BMI at or above the 85th percentile.
Not a fit: Patients with significant cardiac or pulmonary diseases, endocrinologic disorders, or those on certain medications affecting metabolism may not benefit from this study.
Why it matters
Potential benefit: If successful, this study could lead to innovative strategies for preventing type 2 diabetes and improving overall health in children.
How similar studies have performed: Previous studies have shown promising results with short-term interruptions in sedentary behavior, but this approach over multiple days is relatively novel and untested.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: 1. Age 8-11 years-old 2. Good general health 3. BMI≥85th percentile Exclusion Criteria: 1. Significant cardiac or pulmonary disease likely to or resulting in hypoxia or decreased perfusion 2. Diagnosis of T2DM and/or presence of other endocrinologic disorders leading to obesity (e.g., Cushing Syndrome) 3. Current or past anti-psychotic drug use that would affect metabolism 4. Non-diet treatment for hypertension or dyslipidemia 5. Precocious puberty and/or receiving androgen and estrogen therapy 6. Medication use known to affect body composition/weight
Where this trial is running
Los Angeles, California
- Britni Ryan Belcher, PhD, MPH — Los Angeles, California, United States (Recruiting)
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.