Clinical trial Recruiting at 1 site Interventional Ages 18 to 65

Effects of brain stimulation on cognitive task performance

Official title: Brain Stimulation Effects on Cognitive Task Performance

Run by Colorado State University · NCT05556655 · Data updated 2026-11-12

This study tests if a type of brain stimulation can help improve attention, learning, and memory in people while they do thinking tasks.

Quick facts

Study typeInterventional
Ages18 Years to 65 Years
SexAll
Enrollment100 (estimated)
SponsorColorado State University
Academic / other
Locations1 site (Fort Collins, Colorado)
StatusRecruiting
StartedApril 20, 2023
Main results expectedJanuary 1, 2028
Study endsJanuary 1, 2028
Registry record updatedApril 8, 2026
Trial IDNCT05556655 on ClinicalTrials.gov

Is this trial a fit for you?

Likely a good fit

Ideal candidates are right-handed individuals fluent in English without significant medical or neurological conditions.

Probably not a fit

Patients with a history of seizures, significant neurological diagnoses, or psychiatric disorders may not benefit from this study.

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This study investigates how transcranial magnetic stimulation (TMS) can influence cognitive functions such as attention, learning, and memory. Participants will engage in cognitive tasks while receiving either active or sham TMS to determine the optimal design parameters for measuring TMS effects on cognition. The study aims to resolve methodological issues related to task design in TMS research, using a factorial design to identify the best combination of task and TMS settings for reliable behavioral outcomes.

Why it matters

Potential benefit: If successful, this study could enhance cognitive functioning in individuals with neuropsychiatric conditions by optimizing TMS protocols.

How similar studies have gone: Other studies using TMS have shown promise in improving cognitive functions, suggesting potential success for this approach.

Who can join: the full rules

Show full inclusion / exclusion criteria
Inclusion Criteria:

* Right-handed
* Fluent in English

Exclusion Criteria:

* History of seizures or epilepsy
* Family history of epilepsy
* Significant medical or neurological diagnoses
* History of common headache or migraine
* History of common or recent syncope
* History of moderate/severe, multiple mild, or past 12 months head injury
* History of psychiatric, psychological, or neurodevelopmental disorder
* History of alcohol or recreational drug abuse or dependence
* Current visual or hearing difficulties that interfere with cognitive testing
* History of cochlear implants
* Current pregnancy
* History of metal in the head or neck (except braces and fillings)
* Current non-removable piercings in the neck or head
* History of implanted neurostimulator
* History of cardiac pacemaker or intracardiac lines
* History of medication infusion device
* Current use of medications that increase the excitability of the brain
* History of problems with TMS or MRI procedures
* History of EEG for suspected epilepsy
* Alcohol or recreational drug use in the 48 hours prior to TMS
* Inadequate sleep in the 48 hours prior to TMS
* Headache or feeling faint in the 24 hours prior to TMS.

Where it's running

  • Colorado State University Department of Psychology
    Fort Collins, Colorado, United States
    Recruiting

Study contacts

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

How to take part

  1. Review the eligibility criteria above with your treating physician.
  2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
  3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.