Effects of brain stimulation on cognitive task performance
Brain Stimulation Effects on Cognitive Task Performance
NA · Colorado State University · NCT05556655
This study tests if a type of brain stimulation can help improve attention, learning, and memory in people while they do thinking tasks.
Quick facts
| Phase | NA |
|---|---|
| Study type | Interventional |
| Enrollment | 100 (estimated) |
| Ages | 18 Years to 65 Years |
| Sex | All |
| Sponsor | Colorado State University (other) |
| Locations | 1 site (Fort Collins, Colorado) |
| Trial ID | NCT05556655 on ClinicalTrials.gov |
What this trial studies
This study investigates how transcranial magnetic stimulation (TMS) can influence cognitive functions such as attention, learning, and memory. Participants will engage in cognitive tasks while receiving either active or sham TMS to determine the optimal design parameters for measuring TMS effects on cognition. The study aims to resolve methodological issues related to task design in TMS research, using a factorial design to identify the best combination of task and TMS settings for reliable behavioral outcomes.
Who should consider this trial
Good fit: Ideal candidates are right-handed individuals fluent in English without significant medical or neurological conditions.
Not a fit: Patients with a history of seizures, significant neurological diagnoses, or psychiatric disorders may not benefit from this study.
Why it matters
Potential benefit: If successful, this study could enhance cognitive functioning in individuals with neuropsychiatric conditions by optimizing TMS protocols.
How similar studies have performed: Other studies using TMS have shown promise in improving cognitive functions, suggesting potential success for this approach.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * Right-handed * Fluent in English Exclusion Criteria: * History of seizures or epilepsy * Family history of epilepsy * Significant medical or neurological diagnoses * History of common headache or migraine * History of common or recent syncope * History of moderate/severe, multiple mild, or past 12 months head injury * History of psychiatric, psychological, or neurodevelopmental disorder * History of alcohol or recreational drug abuse or dependence * Current visual or hearing difficulties that interfere with cognitive testing * History of cochlear implants * Current pregnancy * History of metal in the head or neck (except braces and fillings) * Current non-removable piercings in the neck or head * History of implanted neurostimulator * History of cardiac pacemaker or intracardiac lines * History of medication infusion device * Current use of medications that increase the excitability of the brain * History of problems with TMS or MRI procedures * History of EEG for suspected epilepsy * Alcohol or recreational drug use in the 48 hours prior to TMS * Inadequate sleep in the 48 hours prior to TMS * Headache or feeling faint in the 24 hours prior to TMS.
Where this trial is running
Fort Collins, Colorado
- Colorado State University Department of Psychology — Fort Collins, Colorado, United States (RECRUITING)
Study contacts
- Study coordinator: Michael Thomas, PhD
- Email: Michael.L.Thomas@colostate.edu
- Phone: (970) 491-6820
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.
Conditions: Cognitive Function, Transcranial Magnetic Stimulation, TMS