Effects of a new supplement on exercise and brain function
The Effects of a Novel Mitochondrial Substrate Supplement on Exercise Performance and Cognitive Function
NA · University of Exeter · NCT06374641
This study is testing a new supplement to see if it can improve exercise performance and brain function in both young and older adults.
Quick facts
| Phase | NA |
|---|---|
| Study type | Interventional |
| Enrollment | 40 (estimated) |
| Ages | 18 Years to 65 Years |
| Sex | All |
| Sponsor | University of Exeter (other) |
| Locations | 1 site (Exeter, Devon) |
| Trial ID | NCT06374641 on ClinicalTrials.gov |
What this trial studies
This clinical trial investigates the impact of a novel mitochondrial substrate supplement on exercise performance and cognitive function over a 16-day period. It involves 40 healthy participants divided into two age groups: young adults (18-30) and older adults (50-65). Participants will undergo a series of cognitive and exercise tests, including blood sample collection, across five lab visits. The study employs a randomized, placebo-controlled, cross-over design to compare the supplement's effects against a placebo.
Who should consider this trial
Good fit: Ideal candidates are healthy individuals aged 18-30 or 50-65 who can perform intense exercise and are not overweight or obese.
Not a fit: Patients aged 31-49 or 66 and older, those with underlying health conditions, or individuals who are overweight or obese may not benefit from this study.
Why it matters
Potential benefit: If successful, this study could enhance exercise performance and cognitive function in healthy individuals.
How similar studies have performed: While the individual components of the supplement are known, this specific combination has not been tested in previous studies, making it a novel approach.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * Participants will be deemed eligible to participate provided they are willing and able to follow the study instructions and 1. are able to take part in intense exercise (as assessed via Physical Activity Readiness Questionnaire (PARQ)) 2. are able to consume a dietary supplement 3. are not overweight/obese (assessed by BMI) 4. do not have any cardiovascular, respiratory, metabolic or musculoskeletal disorders, or any other contraindication to the performance of maximal exercise. Exclusion Criteria: 1. Aged 31-49 and aged 66+. 2. underlying illness or injury (assessed via PARQ) 3. overweight or obese individuals (BMI of \>30 kg.m-2). 4. Cardiovascular, respiratory, metabolic or musculoskeletal disorders (assessed by screening form). 5. Use of dietary supplements, tobacco smoking. 6. Pregnant
Where this trial is running
Exeter, Devon
- Richards Building St. Lukes Campus University of Exeter — Exeter, Devon, United Kingdom (RECRUITING)
Study contacts
- Principal investigator: Andy M Jones, PhD, DSc — University of Exeter
- Study coordinator: Jimmy T Wangdi, PhD
- Email: j.Wangdi4@exeter.ac.uk
- Phone: 441392 661000
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.
Conditions: Exercise Performance, Cognitive Function, choline, nicotinamide, succinate, supplement, exercise, cognitive function