Effect of Tranexamic Acid on Bleeding in Cardiac Surgery

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This clinical trial investigates the impact of different doses of tranexamic acid and activated clotting time (ACT) levels on bleeding and blood transfusion requirements in adult patients undergoing cardiac surgery. Participants will be divided into four groups based on their tranexamic acid dosage and ACT levels during surgery. The primary outcome measured will be the volume of postoperative bleeding within 24 hours. The study aims to enhance understanding of pharmacological management during cardiac procedures.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* adult, cardiac surgery with cardiopulmonary bypass

Exclusion Criteria:

* pregnant
* emergency procedure
* immune compromised
* aortic surgery
* end-stage renal disease
* liver disease
* critical status
* incomplete clinical data

Where it's running

• Taichung Veterans General Hospital
  Taichung, Taiwan Recruiting
• Taichung Veterans General hospital
  Taichung, Taiwan Recruiting

Study contacts

• Study coordinator: Yung-Szu Wu, MD
• Email: adconvert98@gmail.com
• Phone: 0423592525

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

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• Preventive Narrative Exposure for PTSD After Cardiac Surgery in the ICU

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• Impact of cardiopulmonary bypass on platelet lipids and bleeding after cardiac surgery

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• Transcutaneous auricular vagus nerve stimulation to prevent kidney injury after heart surgery

  This trial tests whether applying a non-invasive ear stimulation (taVNS) around the time of elective heart surgery can help prevent acute kidney injury in adults undergoing cardiopulmonary bypass.

  Recruiting Sir Run Run Shaw Hospital · Hangzhou, Zhejiang · NCT07549243

How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.