Effect of Tart Cherry and Aronia Extracts on Heart and Exercise in Endurance Men
Official title: Effects of Oral Supplementation With a Double-Standardized Extract of Tart Cherry (Prunus Cerasus (Vistula)) and Aronia Berry (Aronia Melanocarpa (Michaux)) on Selected Physiological Parameters in Healthy Endurance-Trained Men
Run by Wroclaw Medical University · NCT07885098 · Data updated 2026-11-12
This study tests whether four weeks of CHG SPORT, a tart cherry and aronia extract, improve cardiovascular regulation and exercise performance in healthy endurance-trained men aged 40–75 when compared with placebo.
Quick facts
| Study type | Interventional |
|---|---|
| Ages | 40 Years to 75 Years |
| Sex | Men only |
| Enrollment | 25 (estimated) |
| Sponsor | Wroclaw Medical University Academic / other |
| Locations | 1 site (Wroclaw) |
| Status | Recruiting |
| Started | November 9, 2026 |
| Main results expected | June 30, 2027 |
| Study ends | August 30, 2027 |
| Registry record updated | November 10, 2026 |
| Trial ID | NCT07885098 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Ideal candidates are healthy, endurance-trained men aged 40–75 without cardiovascular disease or the listed exclusions, who regularly train and can complete CPET testing.
✕Probably not a fit
Individuals with cardiovascular disease, metabolic disorders, significant liver or GI disease, or recent use of high-polyphenol supplements may not benefit.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
This randomized, double-period crossover trial examines the effects of four weeks of CHG SPORT supplementation versus placebo on cardiovascular and ventilatory function in healthy endurance-trained men aged 40 to 75. Participants will receive both interventions in random order, separated by a four-week washout, with assessments including resting hemodynamics, responses to transient hypoxia, vascular function, skin glycation markers, CPET performance, 24-hour blood pressure, and blood biomarkers. The study aims to determine if CHG SPORT can modulate cardiopulmonary regulation and exercise capacity beyond placebo. All procedures are conducted in a controlled lab setting at Wroclaw Medical University, with 25 participants enrolled.
Why it matters
Potential benefit: If successful, CHG SPORT could modestly enhance cardiovascular regulation and exercise performance in older, endurance-trained men.
How similar studies have gone: Previous research suggests polyphenol-rich berry extracts can influence vascular function, but results for performance metrics in this exact combination and design are variable and this crossover trial contributes novel evidence.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: * Male sex * Age 40 to 75 years * Active participation in endurance sports, including running, cycling, or other - endurance disciplines, with at least two training sessions per week Exclusion Criteria: * Cardiovascular disease * Diabetes mellitus * Liver or gastrointestinal disease * Cancer * Inflammatory disease * Chronic use of anti-inflammatory medications * Alcohol or drug abuse * Current tobacco smoking * Autoimmune disease * Acute infection within two months before planned study participation * Use of dietary supplements containing high amounts of polyphenols within two months before planned study participation * Lack of written informed consent
Where it's running
-
Department of Physiology and Pathophysiology, Wroclaw Medical University
Wroclaw, Poland Recruiting
Study contacts
- Principal investigator: Bartłomiej Paleczny, PhD, DSc — Wroclaw Medical University, Department of Physiology and Pathophysiology
- Study coordinator: Bartłomiej Paleczny, PhD, DSc
- Email: bartlomiej.paleczny@umw.edu.pl
- Phone: (+48) 71 784 14 37
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How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.