Effect of medical weight loss on pelvic floor dysfunction in overweight women

Effect of Medical Weight Loss on Pelvic Floor Dysfunction: a Prospective Observational Study

Observational Peking Union Medical College Hospital · NCT05987085

This study is testing if a weight loss program can help overweight women feel better by reducing their pelvic floor problems.

Quick facts

Study typeObservational
Enrollment200 (estimated)
Ages18 Years and up
SexFemale
SponsorPeking Union Medical College Hospital Academic / other
Locations1 site (Beijing, Beijing)
Trial IDNCT05987085 on ClinicalTrials.gov

What this trial studies

This observational study aims to investigate how medical weight loss impacts symptoms of pelvic floor dysfunction in obese and overweight women. Participants will follow a weight loss plan that includes diet and exercise, with the goal of determining if these interventions lead to improvements in their pelvic floor symptoms. The study will track changes in symptoms and overall health as participants adhere to the prescribed weight loss regimen.

Who should consider this trial

Good fit: Ideal candidates for this study are women aged 18 and older with a BMI of 24 kg/m2 or higher who are willing to follow a physician-directed weight loss plan.

Not a fit: Patients with recent urinary tract infections, severe systemic diseases, or a history of pelvic floor disorders may not benefit from this study.

Why it matters

Potential benefit: If successful, this study could provide a non-surgical approach to alleviate pelvic floor dysfunction symptoms in overweight women.

How similar studies have performed: While there is limited data on this specific approach, similar studies have suggested that weight loss can positively affect pelvic floor health, indicating potential for success.

Eligibility criteria

Show full inclusion / exclusion criteria
Inclusion Criteria:

* Age 18 or higher
* BMI 24 kg/m2 or higher
* Willing to follow the weight loss plan set by the physician follow-up and complete this study

Exclusion Criteria:

* Urinary tract infection or gynecologic reproductive system infection in the past month
* Treatment history of pelvic floor disorders
* Pregnancy or delivery in the past half year
* Women with severe systemic disease
* No follow-up conditions

Where this trial is running

Beijing, Beijing

How to participate

  1. Review the eligibility criteria above with your treating physician.
  2. Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
  3. Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.
Conditions Weight LossPelvic Floor Disorders
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.