Effect of a new sealer activation method on pain after root canal treatment
The Effect of XP-Endo Finisher Activation of Bioceramic Sealer on Postoperative Pain in Mandibular First Molar With Symptomatic Irreversible Pulpitis
This study is testing if using a special tool to activate a sealer during root canal treatment can help reduce pain for patients with severe tooth pain.
Quick facts
| Phase | Not applicable |
|---|---|
| Study type | Interventional |
| Enrollment | 30 (estimated) |
| Ages | 18 Years to 40 Years |
| Sex | All |
| Sponsor | Future University in Egypt Academic / other |
| Locations | 1 site (Cairo, New Cairo) |
| Trial ID | NCT06640231 on ClinicalTrials.gov |
What this trial studies
This clinical trial investigates the impact of activating a bioceramic sealer using the XP-Endo Finisher on postoperative pain in patients undergoing root canal treatment for symptomatic irreversible pulpitis. The study compares the pain levels in patients who receive the sealer activation against those who have their canals obturated directly without this activation. The goal is to determine if this innovative approach can enhance the effectiveness of root canal sealing and improve patient outcomes. Participants will be monitored for pain levels following the procedure to assess the efficacy of the treatment.
Who should consider this trial
Good fit: Ideal candidates are healthy adults aged 18 to 40 with symptomatic irreversible pulpitis in mandibular first molars.
Not a fit: Patients with severe systemic health issues, those on certain medications, or with specific dental conditions may not benefit from this study.
Why it matters
Potential benefit: If successful, this approach could significantly reduce postoperative pain for patients undergoing root canal treatment.
How similar studies have performed: While the use of bioceramic sealers is gaining popularity, this specific activation method has not been widely tested, making it a novel approach.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * Age ranges from 18 to 40 years old. * No sex predilection. * Patients seeking root canal treatment. * Systematically healthy patient (ASA I, II). * Patient who can understand numerical rate scale and sign an informed consent. * Mandibular first molar teeth with: * Preoperative sharp (moderate or severe) pain. * Vital response of pulp tissue to cold pulp tester (ethyl chloride spray). * Normal periapical radiographic appearance. Exclusion Criteria: * Patients with American association of anesthesiologists (ASA) classification other than ASA T\& II. * Patients who have already ingested preoperative medication, such as analgesics, non-steroidal or steroidal anti-inflammatory drugs, within 12 hours of the start of treatment. * Patients with NSAIDs allergy. * Patients having two or more adjacent teeth needing root canal therapy. * Pregnant patients. * Patients with bleeding disorder. * Patients with long term corticosteroid use * Teeth having; * Necrotic pulp. * History or presence of swelling or fistulous tract. * Acute / chronic periapical abscess. * Mobility more than grade 1. * Pocket depth more than 5mm. * No possible restorability. * Previous root canal treatment. * Periapical radiolucency. * External or internal resorption. * Vertical root fracture. * TMJ problems, bruxism, clenching or traumatic occlusion. * Inability to understand and perform the given instructions.
Where this trial is running
Cairo, New Cairo
- Future University in Egypt — Cairo, New Cairo, Egypt (Recruiting)
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.