Early postpartum treatments to reduce PTSD: written exposure versus capnometry-guided breathing

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

Researchers will enroll women aged 18 and older who delivered a live infant within five days and have elevated PTSD symptoms (PCL-5 ≥28) following severe maternal morbidity or a neonatal ICU admission. Participants will be assigned to written exposure therapy, a capnometry-guided breathing intervention, or usual care, with interventions delivered in the early postpartum period. Written exposure involves short, structured writing sessions about the traumatic birth, while capnometry-guided breathing uses device feedback to regulate breathing and CO2 levels. PTSD symptoms and related outcomes will be measured over time to compare symptom change between groups.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* Age ≥18
* Delivered a live infant within 5 days
* Severe maternal morbidity or infant admitted to NICU
* PCL-5 ≥28
* English-speaking
* Able to consent and participate

Exclusion Criteria:

* Active psychosis or mania
* Current suicidal crisis
* Current suicidal intent or plan
* Cognitive impairment preventing participation

Where it's running

• Stanford University
  Palo Alto, California, United States Recruiting
• University of Arkansas for Medical Sciences
  Little Rock, Arkansas, United States Not yet recruiting

Study contacts

• Principal investigator: Pervez Sultan — Stanford University

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.