Early post-operative colonoscopy to detect anastomotic leakage after low colorectal cancer surgery

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

Patients undergoing colorectal cancer surgery will be assigned to receive an early postoperative colonoscopy within 5–8 days after surgery, and results will be compared to standard care to see if leakage is diagnosed earlier. The study will look at the time to detect anastomotic leakage and whether early endoscopic treatment can be started sooner, potentially reducing complications and reoperations. The approach uses electronic colonoscopy as the intervention to identify leakage promptly. Eligibility includes adults 18–80 with colorectal adenocarcinoma, tumor distance ≤15 cm from the anal verge, and completed primary anastomosis. Exclusion criteria cover metastasis, poor intraoperative findings, contraindications to enteroscopy, pregnancy, prior colorectal surgery (other than polypectomy), and inability to consent.

Why it matters

Who can join: the full rules

Inclusion Criteria:

1. Age 18-80 years old.
2. Pathologically diagnosed as colorectal adenocarcinoma.
3. The distance between the lower edge of the tumor and the anal verge is ≤15cm.
4. Accept laparoscopic or open radical resection and complete primary colorectal or colosal anastomosis.
5. Voluntarily participate and sign the written informed consent.

Exclusion Criteria:

1. Distant metastasis was confirmed by emergency operation, palliative operation or intraoperative metastasis (M1).
2. Unsatisfactory anastomosis or poor blood circulation were found during the operation, and reinforcement suture or preventive colostomy were performed during the operation.
3. There are serious contraindications for enteroscopy (such as acute myocardial infarction, severe cardiopulmonary insufficiency, blood coagulation dysfunction, etc.).
4. Pregnant or lactating women.
5. Previous history of colorectal surgery (except endoscopic polypectomy).
6. Unable to understand or cooperate with the research process.

Where it's running

• Beijing Anzhen Hospital Nanchong Hospital Affiliated to Capital Medical University
  Nanchong, Sichuan, China Recruiting

Study contacts

• Study coordinator: Yunhong Tian, Doctor
• Email: drtianyunhong@126.com
• Phone: 86+13508087719

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.