Early Motor–Cognitive Training after Aneurysmal Subarachnoid Hemorrhage
Official title: The Efficacy of Early Motor-Cognitive Integrative Training on Cognitive and Motor Performance in Patients With Aneurysmal Subarachnoid Hemorrhage
Run by National Taiwan University Hospital · NCT07588997 · Data updated 2026-11-12
Aims to see if early motor-cognitive training can improve thinking and movement in adults who recently had an aneurysmal subarachnoid hemorrhage.
Quick facts
| Study type | Interventional |
|---|---|
| Ages | 18 Years and up |
| Sex | All |
| Enrollment | 18 (estimated) |
| Sponsor | National Taiwan University Hospital Academic / other |
| Locations | 1 site (Taipei) |
| Status | Recruiting |
| Started | November 23, 2025 |
| Main results expected | August 2027 |
| Study ends | December 2027 |
| Registry record updated | November 6, 2026 |
| Trial ID | NCT07588997 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Adults over 18 with acute aneurysmal SAH (2–7 days since intervention), MoCA < 26, able to stand for at least 30 seconds, and WFNS 1–5.
✕Probably not a fit
Patients with unstable vital signs, other neurological conditions, or insufficient education level may not benefit and could be excluded.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
This interventional study tests early motor-cognitive integrated training (e-MCIT) combined with early mobilization to see if it improves cognitive and motor performance after aneurysmal subarachnoid hemorrhage. Eligible participants are adults 18 or older with acute SAH (2–7 days since intervention) and a Montreal Cognitive Assessment below 26. The approach emphasizes coordinated tasks that engage both movement and thinking to potentially enhance neural recovery and daily functioning. Outcomes will focus on cognitive domains such as memory, attention, and executive function, along with motor abilities relevant to activities of daily living.
Why it matters
Potential benefit: If successful, participants may experience better cognitive function and easier return to daily activities and work.
How similar studies have gone: Previous work suggests motor-focused rehabilitation can aid recovery, but clear evidence for combined motor-cognitive training in this specific population is limited.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: * (1) Diagnosis of spontaneous SAH resulting from aneurysm rupture confirmed by either CT scan or angiography. (2) Onset of stroke occurring in the acute phase, specifically 2-7 days after medical intervention. (3) Participants must be over 18 years old. (4) WFNS: 1-5. (5) Able to stand above 30 seconds. (6) Montreal Cognitive Assessment (MoCA)\<26. Exclusion Criteria: * (1)unstable vital sign. (2)patients evaluated as unsuitable by their attending physician. (3)those with other neurological diseases that might interfere with the experiment. (4)less than 12 years of education will be excluded from this study.
Where it's running
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School and Graduate Institute of Physical Therapy, College of Medicine, National Taiwan University
Taipei, Taiwan Recruiting
Study contacts
- Study coordinator: Yan-ci Liu
- Email: yanciliu@ntu.edu.tw
- Phone: +886 33668135
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How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.