Early lymphatic monitoring to help prevent lymphoedema in cancer patients
Subclinical Assessment and Monitoring of Lymphatic System Function in Oncology Patients as Part of Physiotherapeutic Prevention of Limb Lymphoedema
This project will test whether regular lymphatic monitoring with bioimpedance spectroscopy can catch early changes and help prevent lymphoedema in adults treated for cancer.
Quick facts
| Study type | Observational |
|---|---|
| Enrollment | 600 (estimated) |
| Ages | 18 Years and up |
| Sex | All |
| Sponsor | The Greater Poland Cancer Centre Academic / other |
| Locations | 1 site (Poznan, Greater Poland Voivodeship) |
| Trial ID | NCT07011316 on ClinicalTrials.gov |
What this trial studies
This is an observational program that uses noninvasive bioimpedance spectroscopy to monitor subclinical lymphatic function in adult oncology patients at the Greater Poland Cancer Centre. Participants who meet inclusion criteria will undergo periodic measurements to identify early fluid changes before visible swelling occurs. The protocol excludes patients with implanted electronic devices, significant cardiac arrhythmias, or other contraindications that interfere with the measurement technique. The goal is to identify early lymphatic dysfunction to enable timely interventions and reduce progression to clinically apparent lymphoedema.
Who should consider this trial
Good fit: Ideal candidates are adults (≥18) receiving care in participating departments at the Greater Poland Cancer Centre who can stand independently for 30 seconds and can provide informed consent.
Not a fit: Patients with pacemakers or other implanted electronic devices, significant arrhythmias, advanced heart failure, pregnancy, critical limb ischemia, or who cannot stand for 30 seconds are excluded and unlikely to benefit from this monitoring approach.
Why it matters
Potential benefit: If successful, earlier detection could allow timely interventions that reduce the incidence and severity of cancer-related lymphoedema.
How similar studies have performed: Similar approaches using bioimpedance spectroscopy have shown promise for early detection and prevention of breast cancer–related lymphoedema, though evidence across other cancer types is more limited.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * admission to the Greater Poland Cancer Centre for treatment in one of the departments participating in the study, * age ≥ 18 years, * ability to balance independently in a standing position for 30 seconds, * obtaining the patient's written informed consent to participate in the study. Exclusion Criteria: * age ≤ 18 years, * cardiac arrhythmia, * pacemakers or other implanted electronic devices, * history of external defibrillation, * pregnancy, * critical limb ischaemia, * advanced heart failure (NYHA III and IV0), * symptoms of deep vein thrombosis, * uncompensated heart, kidney or thyroid failure, * peripheral nerve damage, * presence of psychiatric disorders that preclude informed consent or limit appropriate co-operation of the patient, * lack of informed consent from the patient to participate in the study.
Where this trial is running
Poznan, Greater Poland Voivodeship
- The Greater Poland Cancer Centre — Poznan, Greater Poland Voivodeship, Poland (Recruiting)
Study contacts
- Principal investigator: Janusz Doś, PT, PhD — The Greater Poland Cancer Centre
- Study coordinator: Ewa Tańska, PhD
- Email: ewa.tanska@wco.pl
- Phone: +48618850767
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.