Dynamic hormone profiling for diagnosing primary aldosteronism

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This observational study utilizes a 24-hour microdialysis methodology to perform dynamic multisteroid adrenal hormone profiling in patients with suspected or confirmed primary aldosteronism (PA). It aims to capture the rhythmic nature of aldosterone and related hormones while simultaneously monitoring blood pressure, glucose levels, sleep patterns, activity levels, and food intake. The goal is to develop a novel, sensitive, and user-friendly diagnostic procedure that improves upon the current cumbersome diagnostic methods for PA. By comparing hormone profiling results with various physiological parameters, the study seeks to enhance the understanding and diagnosis of PA.

Why it matters

Who can join: the full rules

Inclusion criteria Age 18 to 70 years Suspected PA admitted for diagnostic saline infusion testing or confirmed PA diagnosis according to Endocrine Society criteria.. Written informed consent

Exclusion criteria

* Age \<18 or \> 70 years.
* Pregnancy.
* Known adrenal failure and/or on steroid therapy (oral, inhaled, parenteral or topical) or other interfering medication.

Where it's running

• Haukeland University Hospital
  Bergen, Norway Recruiting

Study contacts

• Principal investigator: Marianne Aarda Grytaas, MD PhD — Haukeland University Hospital
• Study coordinator: Marianne Aardal Grytaas, MD PhD
• Email: marianne.grytaas@helse-bergen.no
• Phone: 004741545435

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

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• Metomidate PET-CT vs Usual Care for Primary Aldosteronism

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• Captopril Test with LC-MS/MS for Aldosterone and Renin in Primary Aldosteronism

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.