Dydrogesterone versus GnRH antagonist for women with low ovarian response using double ovarian stimulation

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This phase II randomized trial assigns women in POSEIDON group 4 to either progestin-primed ovarian stimulation with dydrogesterone or a standard GnRH antagonist protocol during double ovarian stimulation. The primary focus is prevention of premature LH surge, with secondary outcomes including ovarian response, embryo yield, and cost-effectiveness. Key exclusions are PCOS, endometriosis, and a history of recurrent abortion. The trial is conducted at Cairo University and Bedaya Hospital in the Cairo/Giza region.

Why it matters

Who can join: the full rules

Inclusion Criteria:

Patients belonging to Poseidon group 4

Exclusion Criteria:

* PCOS
* Endometriosis
* History of recurrent abortion

Where it's running

• Cairo University
  Cairo, Cairo Governorate, Egypt Recruiting
• Bedaya Hospital
  Giza, Egypt Not yet recruiting

Study contacts

• Principal investigator: Samar A Alhofy, M.D, Msc — Cairo University
• Study coordinator: Usama M Fouda, Prof.
• Email: umfrfouda@yahoo.com
• Phone: +201095401375

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.