Dual-endoscope Sentinel Lymph Node Navigation for Early Gastric Cancer

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This interventional study investigates a dual-endoscope assisted approach to sentinel lymph node navigation in early gastric cancer. Patients with tumors limited to the mucosa or submucosa and requiring further surgery after ESD may be enrolled. The procedure combines laparoscopic and endoscopic techniques to map sentinel nodes and guide surgical decisions. Safety and efficacy outcomes will be observed to determine feasibility in this setting. The trial is conducted at the First Hospital of Jilin University in Changchun, China.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* Preoperative assessment indicating that the tumor was confined to the mucosa or submucosa, consistent with the diagnosis of early gastric cancer.
* Patients who required additional surgical intervention following initial endoscopic submucosal dissection (ESD) based on postoperative pathological evaluation.
* Patients and their families fully understood the procedure, requested dual-endoscope assisted sentinel lymph node navigation surgery, agreed to participate in this clinical study, and signed the informed consent form.

Exclusion Criteria:

* Preoperative assessment indicating suspected lymph node or distant metastasis.
* History of complex abdominal surgery rendering laparoscopic treatment infeasible.
* Participation in another clinical trial within 4 weeks prior to enrollment or currently participating in another trial.
* History of severe psychiatric disorders.
* Pregnant or lactating women.
* Uncontrolled infection prior to surgery.
* Presence of other malignancies or comorbidities that may significantly affect survival.
* Any other conditions deemed by the investigators as unsuitable for participation, or refusal by the patient or family to enroll.
* Cardiopulmonary, hepatic, and renal functions were unsufficient to tolerate the surgery.

Where it's running

• the First Hospital of Jilin University
  Changchun, Jilin, China Recruiting
• the First Hospital of Jilin University
  Ch’ang-ch’un, Jilin, China Active not recruiting

Study contacts

• Study coordinator: Quan Wang, Professor
• Email: wquan@jlu.edu.cn
• Phone: 15843073207

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

• SPADE procedure for upper stomach cancer

  A multicenter study will test the SPADE operation, a special stomach reconnection technique, in patients with early upper-stomach cancer undergoing proximal gastrectomy to see if it is safe and feasible.

  Recruiting National Cancer Center, Korea · Goyang, Gyeonggido · NCT07892183

• LECS with sentinel node navigation for early gastric cancer

  This study tests whether combining LECS with sentinel node navigation can treat early gastric cancer while preserving stomach function in eligible patients.

  Recruiting Peking University People's Hospital · Beijing, Beijing Municipality · NCT07857668

• Image-guided platform helps find sentinel lymph nodes in early gastric cancer

  This study tests whether an image-guided platform with a deep learning model can find and retrieve sentinel lymph nodes better than standard palpation in people with early gastric cancer undergoing LECS-SNNS.

  Recruiting Beijing Friendship Hospital · Beijing · NCT07835087

• Early Gastric Cancer in China: Real-World Outcomes by Treatment Type

  This project will look at real-world outcomes for about 5,000 Chinese patients with early gastric cancer treated with endoscopic resection, laparoscopic surgery, open surgery, or a combined approach to see how treatments relate to survival and recurrence.

  Recruiting Beijing Friendship Hospital · Beijing · NCT07747688

• H. pylori status and tissue features to predict gastric cancer behavior after endoscopic treatment

  This study tests whether current H. pylori infection status and tissue features can help predict how early gastric cancer will behave after endoscopic treatment.

  Recruiting at 3 sites Chinese PLA General Hospital · Beijing, Beijing Municipality and 2 other locations · NCT07724496

• Explainable multimodal AI for diagnosing early gastric cancer from endoscopic images

  This project will try an explainable AI that combines white-light and image-enhanced endoscopy pictures plus clinical data to help detect early gastric cancer in adults with suspicious gastric lesions who underwent endoscopic submucosal dissection.

  Recruiting The First Affiliated Hospital of Soochow University · Suzhou · NCT07551466

How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.