Clinical trial Recruiting at 1 site Interventional Ages 18 to 25 Women only

Doppler-guided angiopuncture for menstrual pain

Official title: Doppler Ultrasound-Guided Angiopuncture for Dysmenorrhea Pain: A Clinical Trial

Run by City University of Hong Kong · NCT07176910 · Data updated 2026-11-12

This test tries Doppler ultrasound-guided angiopuncture to reduce period pain in people with primary dysmenorrhea.

Quick facts

Study typeInterventional
Ages18 Years to 25 Years
SexWomen only
Enrollment30 (estimated)
SponsorCity University of Hong Kong
Academic / other
Locations1 site (Changchun)
StatusRecruiting
StartedSeptember 1, 2024
Main results expectedOctober 1, 2025
Study endsNovember 1, 2025
Registry record updatedSeptember 16, 2025
Trial IDNCT07176910 on ClinicalTrials.gov

Is this trial a fit for you?

Likely a good fit

People with primary dysmenorrhea for at least 6 months, numeric pain score ≥2, regular 28–32 day cycles, 4–7 day periods, and no pelvic pathology on transvaginal ultrasound are ideal candidates.

Probably not a fit

People with secondary dysmenorrhea, coagulopathy (INR >1.5), recent analgesic use within 48 hours, or irregular cycles are unlikely to benefit from or be eligible for this procedure.

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This is an interventional, single-arm procedure study using Doppler ultrasound to locate perforator points for angiopuncture in people with primary dysmenorrhea. Participants receive angiopuncture at Doppler-identified sites and pain and safety measures are recorded before and after the procedure. Eligible participants have at least 6 months of menstrual pain with regular 28–32 day cycles and no pelvic pathology on transvaginal ultrasound; those with coagulopathy, recent analgesic use, or secondary dysmenorrhea are excluded. The trial is led by City University of Hong Kong with clinical conduct at The Third Affiliated Hospital of Changchun University of Chinese Medicine.

Why it matters

Potential benefit: If successful, this approach could offer a non-drug option to reduce menstrual pain and lower reliance on analgesics.

How similar studies have gone: Some acupuncture-related and local vascular-targeting techniques have shown pain relief in dysmenorrhea, but Doppler-guided angiopuncture for this condition is relatively novel with limited prior data.

Who can join: the full rules

Show full inclusion / exclusion criteria
Inclusion Criteria:

Primary dysmenorrhea diagnosis (≥6 months of menstrual pain scoring ≥2 on numerical rating scale) Regular menstrual cycles (28-32 days), menstrual period lasts 4 to 7 days No pelvic pathology on transvaginal ultrasound.

Exclusion Criteria:

coagulopathy (INR \>1.5) recent analgesic use (48-hour washout) secondary dysmenorrhea confirmed by laparoscopy.

Where it's running

  • The Third Affiliated Hospital of Changchun University of Chinese Medicine
    Changchun, China
    Recruiting

Study contacts

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How to take part

  1. Review the eligibility criteria above with your treating physician.
  2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
  3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.