Doppler-guided angiopuncture for menstrual pain
Official title: Doppler Ultrasound-Guided Angiopuncture for Dysmenorrhea Pain: A Clinical Trial
Run by City University of Hong Kong · NCT07176910 · Data updated 2026-11-12
This test tries Doppler ultrasound-guided angiopuncture to reduce period pain in people with primary dysmenorrhea.
Quick facts
| Study type | Interventional |
|---|---|
| Ages | 18 Years to 25 Years |
| Sex | Women only |
| Enrollment | 30 (estimated) |
| Sponsor | City University of Hong Kong Academic / other |
| Locations | 1 site (Changchun) |
| Status | Recruiting |
| Started | September 1, 2024 |
| Main results expected | October 1, 2025 |
| Study ends | November 1, 2025 |
| Registry record updated | September 16, 2025 |
| Trial ID | NCT07176910 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
People with primary dysmenorrhea for at least 6 months, numeric pain score ≥2, regular 28–32 day cycles, 4–7 day periods, and no pelvic pathology on transvaginal ultrasound are ideal candidates.
✕Probably not a fit
People with secondary dysmenorrhea, coagulopathy (INR >1.5), recent analgesic use within 48 hours, or irregular cycles are unlikely to benefit from or be eligible for this procedure.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
This is an interventional, single-arm procedure study using Doppler ultrasound to locate perforator points for angiopuncture in people with primary dysmenorrhea. Participants receive angiopuncture at Doppler-identified sites and pain and safety measures are recorded before and after the procedure. Eligible participants have at least 6 months of menstrual pain with regular 28–32 day cycles and no pelvic pathology on transvaginal ultrasound; those with coagulopathy, recent analgesic use, or secondary dysmenorrhea are excluded. The trial is led by City University of Hong Kong with clinical conduct at The Third Affiliated Hospital of Changchun University of Chinese Medicine.
Why it matters
Potential benefit: If successful, this approach could offer a non-drug option to reduce menstrual pain and lower reliance on analgesics.
How similar studies have gone: Some acupuncture-related and local vascular-targeting techniques have shown pain relief in dysmenorrhea, but Doppler-guided angiopuncture for this condition is relatively novel with limited prior data.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: Primary dysmenorrhea diagnosis (≥6 months of menstrual pain scoring ≥2 on numerical rating scale) Regular menstrual cycles (28-32 days), menstrual period lasts 4 to 7 days No pelvic pathology on transvaginal ultrasound. Exclusion Criteria: coagulopathy (INR \>1.5) recent analgesic use (48-hour washout) secondary dysmenorrhea confirmed by laparoscopy.
Where it's running
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The Third Affiliated Hospital of Changchun University of Chinese Medicine
Changchun, China Recruiting
Study contacts
- Principal investigator: Jinlian HU, PhD — City University of Hong Kong
- Study coordinator: Rong HAN, PhD student
- Email: ronghan5-c@my.cityu.edu.hk
- Phone: +852 61448549
Similar studies
Other studies for the same condition or treatment. Recruiting studies are listed first.
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Osteopathic Manipulative Treatment for Dysmenorrhea Symptoms
This pilot study tests whether a targeted OMT session before the next period can reduce pain and other dysmenorrhea symptoms in female university community members.
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Diaphragm-Pelvic Floor Training for Young Women with Menstrual Pain
A randomized trial tests whether Diaphragm-Pelvic Floor Synergy training can reduce menstrual pain and improve quality of life in university-aged women with primary dysmenorrhea.
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This study tests a 12-week digital program with at-home neuromodulation to see if it helps women with menstrual or perimenopausal symptoms feel better at work and in daily life.
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Aerobic Exercise vs. Jacobson’s Relaxation for Primary Dysmenorrhea
This study tests whether aerobic exercise or Jacobson’s progressive relaxation can help reduce pain and fatigue and improve quality of life for young women with primary dysmenorrhea.
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Sacral release versus lumbar mobilization for period cramps in teens.
This will test whether sacral release or lumbar mobilization works better to reduce menstrual pain, lessen symptoms, and improve quality of life in adolescent girls with primary dysmenorrhea.
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This trial will test whether a single IV dose of magnesium sulfate relieves severe menstrual cramp pain in women 18–35 better than IV dexketoprofen.
How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.