Doppler-guided angiopuncture for menstrual pain

Doppler Ultrasound-Guided Angiopuncture for Dysmenorrhea Pain: A Clinical Trial

Not applicable Interventional City University of Hong Kong · NCT07176910

This test tries Doppler ultrasound-guided angiopuncture to reduce period pain in people with primary dysmenorrhea.

Quick facts

PhaseNot applicable
Study typeInterventional
Enrollment30 (estimated)
Ages18 Years to 25 Years
SexFemale
SponsorCity University of Hong Kong Academic / other
Locations1 site (Changchun)
Trial IDNCT07176910 on ClinicalTrials.gov

What this trial studies

This is an interventional, single-arm procedure study using Doppler ultrasound to locate perforator points for angiopuncture in people with primary dysmenorrhea. Participants receive angiopuncture at Doppler-identified sites and pain and safety measures are recorded before and after the procedure. Eligible participants have at least 6 months of menstrual pain with regular 28–32 day cycles and no pelvic pathology on transvaginal ultrasound; those with coagulopathy, recent analgesic use, or secondary dysmenorrhea are excluded. The trial is led by City University of Hong Kong with clinical conduct at The Third Affiliated Hospital of Changchun University of Chinese Medicine.

Who should consider this trial

Good fit: People with primary dysmenorrhea for at least 6 months, numeric pain score ≥2, regular 28–32 day cycles, 4–7 day periods, and no pelvic pathology on transvaginal ultrasound are ideal candidates.

Not a fit: People with secondary dysmenorrhea, coagulopathy (INR >1.5), recent analgesic use within 48 hours, or irregular cycles are unlikely to benefit from or be eligible for this procedure.

Why it matters

Potential benefit: If successful, this approach could offer a non-drug option to reduce menstrual pain and lower reliance on analgesics.

How similar studies have performed: Some acupuncture-related and local vascular-targeting techniques have shown pain relief in dysmenorrhea, but Doppler-guided angiopuncture for this condition is relatively novel with limited prior data.

Eligibility criteria

Show full inclusion / exclusion criteria
Inclusion Criteria:

Primary dysmenorrhea diagnosis (≥6 months of menstrual pain scoring ≥2 on numerical rating scale) Regular menstrual cycles (28-32 days), menstrual period lasts 4 to 7 days No pelvic pathology on transvaginal ultrasound.

Exclusion Criteria:

coagulopathy (INR \>1.5) recent analgesic use (48-hour washout) secondary dysmenorrhea confirmed by laparoscopy.

Where this trial is running

Changchun

Study contacts

How to participate

  1. Review the eligibility criteria above with your treating physician.
  2. Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
  3. Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.
Conditions AngiopunctureDysmenorrheaDopplar Ultrasoundangiopuncturedopplarultrasound
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.