Does continuing alcohol at current levels after catheter ablation affect AF recurrence, QoL, and thinking ability?

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This randomized trial investigates whether continuing current alcohol consumption after catheter ablation for atrial fibrillation influences arrhythmia recurrence, quality of life, and cognitive function. Eligible participants are adults with AF who drink more than five drinks per week and are undergoing a first ablation. The study compares outcomes based on maintaining usual alcohol intake versus modification, with assessments including cognitive testing and QoL measures. The trial is led by the Texas Cardiac Arrhythmia Research Foundation at the Texas Cardiac Arrhythmia Institute and St. David's Medical Center in Austin, TX. Enrollment targets individuals who regularly consume alcohol and meet specific clinical criteria, excluding those with significant comorbidity or cognitive impairment.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* AF patients that regularly consume \>5 alcoholic drink (\*12 g of pure alcohol/drink)/week
* Paroxysmal or persistent AF
* First catheter ablation History of alcohol-induced arrhythmia
* Willing to sign the written informed consent

Exclusion Criteria:

* Binge drinkers (alcohol dependence)
* Non-drinkers
* LVEF \<35%
* Psychiatric conditions
* MoCA score ≤ 17 on Montreal Cognitive Assessment (MoCA)
* Patients with established dementia
* Medically unstable patients (acute/unstable or poorly controlled problems that would demand focused, relatively urgent or emergent medical attention)
* Unwilling for alcohol-abstinence
* Long-standing persistence AF
* Patient under legal protection
* Pregnancy

Where it's running

• Texas Cardiac Arrhythmia Institute, St. David's Medical Center
  Austin, Texas, United States Recruiting

Study contacts

• Principal investigator: Andrea Natale — Texas Cardiac Arrhythmia Institute, St.
• Study coordinator: Andrea Natale
• Email: dr.natale@gmail.com
• Phone: 5125448186

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.