Diode laser added to deep cleaning for gum disease.
Evaluation of the Effect of Adjunctive Diode Laser Therapy in Mechanical Scaling and Root Surface Debridement in Non-Surgical Periodontal Therapy
This test will see if adding a 940-nm diode laser to deep cleaning helps adults with periodontal pockets and attachment loss more than deep cleaning alone.
Quick facts
| Phase | Not applicable |
|---|---|
| Study type | Interventional |
| Enrollment | 20 (estimated) |
| Ages | 18 Years and up |
| Sex | All |
| Sponsor | Tel Aviv University Academic / other |
| Locations | 1 site (Afula, North) |
| Trial ID | NCT07446127 on ClinicalTrials.gov |
What this trial studies
This randomized split-mouth trial compares standard non-surgical root surface debridement (scaling and root planing) alone to the same treatment with adjunctive 940-nm diode laser therapy, with quadrants in each patient randomly assigned to one of the two approaches. Eligible, systemically healthy adults must have at least 20 teeth, at least five teeth per quadrant, ≥30% of sites involved, and at least two teeth per quadrant with probing depths ≥5 mm and radiographic bone loss. Clinical periodontal outcomes such as probing depth reduction and changes in clinical attachment level will be measured to compare effectiveness between treatments. The trial is conducted at a single center affiliated with Tel Aviv University in Afula, Israel.
Who should consider this trial
Good fit: Adults who are systemically healthy, have at least 20 teeth with significant periodontal pockets (≥30% of sites and ≥2 teeth per quadrant with probing depths ≥5 mm) and radiographic bone loss are ideal candidates.
Not a fit: Smokers, people with systemic diseases affecting the periodontium, those on medications that affect periodontal status, pregnant or lactating women, and patients who had periodontal treatment within the past 12 months are excluded and unlikely to benefit from this protocol.
Why it matters
Potential benefit: If successful, adding diode laser therapy could produce greater pocket depth reduction and better attachment level preservation than cleaning alone.
How similar studies have performed: Previous studies of adjunctive diode lasers with scaling and root planing have shown mixed results, with some reporting modest additional pocket depth reduction while overall evidence remains inconclusive.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: 1. Systemically healthy patients 2. Each patient should have more than 20 teeth remaining, and at least 5 teeth per quadrant 3. Each patient presented ≥ 30% of sites involved 4. At least 2 teeth with a probing depth of ≥ 5 mm in each quadrant, with evident radiographic bone loss. Exclusion Criteria: 1. History of systemic diseases affecting the periodontium 2. Smokers and alcoholic patients 3. Use of medication within the last 6 months, which might affect the periodontal status 4. Pregnant and lactating women 5. Patients who had any periodontal treatment ≤ 12 months before the examination.
Where this trial is running
Afula, North
- Dr Younis Mahmoud — Afula, North, Israel (Recruiting)
Study contacts
- Study coordinator: Mahmoud Dr Younis, DMD
- Email: younisma@hotmail.com
- Phone: +972544934823
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.