Digital Prevention Platform for Lifelong Health

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

DELPHI uses wearable sensors, artificial intelligence, federated learning, and the Human Digital Twin concept to collect and interpret data from healthy adults. In a multicenter randomized pilot, 200 participants will be assigned to receive the full DELPHI platform with personalized recommendations and continuous feedback or to a passive monitoring control for up to 12 months. The study aims to see if this digital approach can support healthier lifestyle choices and prevention of chronic diseases. Data will be analyzed to tailor content and measure changes in health-related behaviors and outcomes. The trial is conducted across sites in Southern Italy with collaboration among research and hospital partners.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* Apparent good general health status, confirmed by medical history and initial self-assessment.
* Ability to understand the study information and provide informed consent.
* Availability and motivation to participate for the entire duration of the study (12 months).
* Access to a smartphone compatible with the DELPHI application.
* Willingness to wear the wearable devices for continuous monitoring of physiological parameters.
* Basic familiarity with mobile applications or willingness to receive training on their use.
* Signed informed consent.

Exclusion Criteria:

* Presence of severe chronic diseases in active phase (e.g., oncological, cardiovascular, or neurological diseases).
* Acute or unstable conditions that could compromise participation in the protocol.
* Current pregnancy.
* Diagnosed major cognitive or psychiatric disorders that hinder understanding of or adherence to the protocol.
* Current use of medications that significantly affect the parameters being monitored (e.g., psychotropic drugs, beta-blockers).
* Simultaneous participation in other clinical studies.
* Logistical difficulties that prevent frequent interaction with the platform (e.g., lack of connection, unwillingness to attend periodic follow-ups).

Where it's running

• Institute for Biomedical Research and Innovation (IRIB)-National Reasearch Council (CNR)
  Messina, Italy Recruiting

Study contacts

• Principal investigator: Gennaro Tartarisco — Institute for Biomedical Research and Innovation (IRIB)-National Reasearch Council (CNR)
• Study coordinator: Gennaro Tartarisco
• Email: gennaro.tartarisco@irib.cnr.it
• Phone: +393283377046

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.